Abstract Mixed-lineage kinase 3 (MLK3) is a serine/threonine kinase of the MAPK Kinase
kinase (MAP3K) family that plays critical roles in various biological processes, including …

Abstract Mixed lineage kinase 3 (MLK3) is a serine/threonine kinase family member of
mitogen activated protein kinase kinase kinases (MAP3Ks). MLK3 has been implicated in …

Aim: In the present study boswellic acids-loaded chitosan nanoparticles were synthesized
using ionic gelation technique. The influence of independent variables were studied and …

Prostate cancer (PCa) is one of the most prevalent and malignant cancer types in men,
which causes more than three-hundred thousand cancer death each year. At late stage of …

Background The TRIM5 proteins are cellular restriction factors that prevent retroviral
infection in a species-specific manner. Multiple experiments indicate that restriction activity …

Abstract The transcription factor Glioma-Associated Oncogene Homolog 1 (GLI1) is
activated by sonic hedgehog (SHH) cascade and is an established driver of pancreatic …

Abstract Kruppel-like factor 4 (KLF4), a member of the KLF family of transcription factors, has
been considered as a crucial tumor suppressor in hepatocellular carcinoma (HCC). Using …

Mucuna pruriens (MP) which is commonly known as “Velvet Bean” is an underutilized
legume traditionally used to treat Parkinson's disease and male fertility issues. Extracts of …

Background Metastatic melanoma is a disease with high mortality and limited therapeutic
options. MicroRNAs (miRNAs) can be used to classify melanoma stage. Methods …

Astrocytes react to central nervous system (CNS) injury and participate in gliotic responses,
imparting negative, as well as positive effects on axonal regeneration. Despite the …