Integration of substrate-and flow-derived stresses in endothelial cell mechanobiology
CA Dessalles, C Leclech, A Castagnino… - Communications …, 2021 - nature.com
Endothelial cells (ECs) lining all blood vessels are subjected to large mechanical stresses
that regulate their structure and function in health and disease. Here, we review EC …
that regulate their structure and function in health and disease. Here, we review EC …
Mechanical regulation of the early stages of angiogenesis
S Barrasa-Ramos, CA Dessalles… - Journal of the …, 2022 - royalsocietypublishing.org
Favouring or thwarting the development of a vascular network is essential in fields as
diverse as oncology, cardiovascular disease or tissue engineering. As a result …
diverse as oncology, cardiovascular disease or tissue engineering. As a result …
A 3D‐bioprinted vascularized glioblastoma‐on‐a‐chip for studying the impact of simulated microgravity as a novel pre‐clinical approach in brain tumor therapy
Glioblastoma multiforme (GBM) is one of the most aggressive malignant brain tumors and
urgently requires the development of new therapeutic strategies. In this study, an innovative …
urgently requires the development of new therapeutic strategies. In this study, an innovative …
Biorheological views of endothelial cell responses to mechanical stimuli
M Sato, T Ohashi - Biorheology, 2005 - content.iospress.com
Vascular endothelial cells are located at the innermost layer of the blood vessel wall and are
always exposed to three different mechanical forces: shear stress due to blood flow …
always exposed to three different mechanical forces: shear stress due to blood flow …
Vascular endothelial cell behavior in complex mechanical microenvironments
The vascular mechanical microenvironment consists of a mixture of spatially and temporally
changing mechanical forces. This exposes vascular endothelial cells to both hemodynamic …
changing mechanical forces. This exposes vascular endothelial cells to both hemodynamic …
Hydrostatic pressure influences morphology and expression of VE-cadherin of vascular endothelial cells
T Ohashi, Y Sugaya, N Sakamoto, M Sato - Journal of biomechanics, 2007 - Elsevier
Bovine aortic endothelial cells (BAECs) were exposed to hydrostatic pressures of 50, 100,
and 150mmHg and changes in morphology and expression of vascular endothelial (VE) …
and 150mmHg and changes in morphology and expression of vascular endothelial (VE) …
Regulation of cell behavior by hydrostatic pressure
S Liu, R Tao, M Wang, J Tian… - Applied …, 2019 - asmedigitalcollection.asme.org
Hydrostatic pressure (HP) regulates diverse cell behaviors including differentiation,
migration, apoptosis, and proliferation. Abnormal HP is associated with pathologies …
migration, apoptosis, and proliferation. Abnormal HP is associated with pathologies …
In vitro and in silico evaluations of resin-based dental restorative material toxicity
S Bandarra, P Mascarenhas, AR Luís, M Catrau… - Clinical Oral …, 2020 - Springer
Objectives This study aims to evaluate the cytocompatibility of three provisional restoration
materials and predict neurotoxic potential of their monomers. These materials are Tab …
materials and predict neurotoxic potential of their monomers. These materials are Tab …
Multiplex, high-throughput method to study cancer and immune cell mechanotransduction
AR Fabiano, SC Robbins, SV Knoblauch… - Communications …, 2024 - nature.com
Studying cellular mechanoresponses during cancer metastasis is limited by sample
variation or complex protocols that current techniques require. Metastasis is governed by …
variation or complex protocols that current techniques require. Metastasis is governed by …
[PDF][PDF] Responses of cells to flow in vitro
The response of cells to a flow has been studied in vitro. The response of cells was
examined in two types of flow channels: a circumnutating flow in a donut-shaped open …
examined in two types of flow channels: a circumnutating flow in a donut-shaped open …