Fractures and injuries pertaining to bone tissue usually take prolonged periods for its natural
healing. To overcome this problem, the field of bone tissue engineering (BTE) has acquired …

Periodontitis, a bacterium-induced inflammatory disease that is characterized by alveolar
bone loss, is highly prevalent worldwide. Elucidating the underlying mechanisms of alveolar …

Reconstruction of large bone defects remains problematic in orthopedic and craniofacial
clinical practice. Autografts are limited in supply and are associated with donor site morbidity …

Biofilm-associated diseases are one of the main causes of implant failure. Currently, the
development of implant surface treatment goes beyond the osseointegration process and …

This study reports on scaffold-based periodontal tissue engineering in a large preclinical
animal model. A biphasic scaffold consisting of bone and periodontal ligament …

Mesenchymal stem cells (MSCs) represent a heterogeneous population of progenitor cells
with self-renewal and multipotent differentiation potential. Aside from their regenerative role …

Cell-based therapy is considered a promising approach to achieving predictable periodontal
regeneration. In this study, the regenerative potential of cell sheets derived from different …

Adult human gingival fibroblasts (HGFs), the most abundant cells in the oral cavity, are
essential for maintaining oral homeostasis. Compared with other tissues, adult oral mucosal …

Human teeth contain a variety of mesenchymal stem cell populations that could be used for
cell-based regenerative therapies. However, the isolation and potential use of these cells in …

The murine-derived MC3T3-E1 cell line provided by the American Type Culture Collection
(ATCC) is a well-known osteogenic cell culture model system to test materials in vitro …