Antimicrobial blue light: A 'Magic Bullet'for the 21st century and beyond?

LG Leanse, C Dos Anjos, S Mushtaq, T Dai - Advanced drug delivery …, 2022 - Elsevier
Over the past decade, antimicrobial blue light (aBL) at 400− 470 nm wavelength has
demonstrated immense promise as an alternative approach for the treatment of multidrug …

The Parameters Affecting Antimicrobial Efficiency of Antimicrobial Blue Light Therapy: A Review and Prospect

S Huang, S Lin, H Qin, H Jiang, M Liu - Biomedicines, 2023 - mdpi.com
Antimicrobial blue light (aBL) therapy is a novel non-antibiotic antimicrobial approach which
works by generating reactive oxygen species. It has shown excellent antimicrobial ability to …

[HTML][HTML] Antimicrobial 405 nm violet-blue light treatment of ex vivo human platelets leads to mitochondrial metabolic reprogramming and potential alteration of …

S Jana, MR Heaven, N Dahiya, C Stewart… - … of Photochemistry and …, 2023 - Elsevier
Continued efforts to reduce the risk of transfusion-transmitted infections (TTIs) through blood
and blood components led to the development of ultraviolet (UV) light irradiation …

Violet‐blue 405‐nm Light‐based Photoinactivation for Pathogen Reduction of Human Plasma Provides Broad Antibacterial Efficacy Without Visible Degradation of …

CF Stewart, RM Tomb, HJ Ralston… - Photochemistry and …, 2022 - Wiley Online Library
In transfusion medicine, bacterial contamination can occur in ex vivo stored blood plasma,
and there are continued efforts to improve blood safety and reduce the risk of transfusion …

Visible 405 nm violet-blue light successfully inactivates HIV-1 in human plasma

V Ragupathy, M Haleyurgirisetty, N Dahiya, C Stewart… - Pathogens, 2022 - mdpi.com
Despite significant advances in ensuring the safety of the blood supply, there is continued
risk of transfusion transmitted infections (TTIs) from newly emerging or re-emerging …

[HTML][HTML] Human platelet concentrates treated with microbicidal 405 nm light retain hemostasis activity

JW Jackson, PR Kaldhone, LA Parunov… - … of Photochemistry and …, 2024 - Elsevier
Chemical and UV light-based pathogen reduction technologies are currently in use for
human platelet concentrates (PCs) to enhance safety from transfusion-transmitted infections …

The Preclinical Validation of 405 nm Light Parasiticidal Efficacy on Leishmania donovani in Ex Vivo Platelets in a Rag2−/− Mouse Model

PR Kaldhone, N Azodi, HL Markle, N Dahiya, C Stewart… - Microorganisms, 2024 - mdpi.com
Violet–blue light of 405 nm in the visible spectrum at a dose of 270 J/cm2 alone has been
shown to be an effective microbicidal tool for inactivating several bacteria, HIV-1, and …

The importance of estimating the burden of disease from foodborne transmission of Trypanosoma cruzi

LJ Robertson, AH Havelaar, KH Keddy… - PLOS Neglected …, 2024 - journals.plos.org
Chagas disease (ChD), caused by infection with the flagellated protozoan, Trypanosoma
cruzi, has a complicated transmission cycle with many infection routes. These include vector …

[HTML][HTML] Effectiveness of front line and emerging fungal disease prevention and control interventions and opportunities to address appropriate eco-sustainable …

M Garvey, E Meade, NJ Rowan - Science of the Total Environment, 2022 - Elsevier
Fungal pathogens contribute to significant disease burden globally; however, the fact that
fungi are eukaryotes has greatly complicated their role in fungal-mediated infections and …

405 nm violet-blue light inactivates hepatitis C cell culture virus (HCVcc) in ex vivo human platelet concentrates and plasma

JW Jackson, PR Kaldhone, C Stewart, J Anderson… - Scientific Reports, 2024 - nature.com
Added safety measures coupled with the development and use of pathogen reduction
technologies (PRT) significantly reduces the risk of transfusion-transmitted infections (TTIs) …