Oxidative and inflammatory imbalance in placenta and kidney of sFlt1-induced early-onset preeclampsia rat model

Á Santana-Garrido, C Reyes-Goya, P Espinosa-Martín… - Antioxidants, 2022 - mdpi.com
Preeclampsia (PE) is a pregnancy-specific disorder characterized by the new onset of
hypertension plus proteinuria and/or end-organ dysfunction. Here, we investigate the role of …

Exploring the Potential of Wild Olive (Acebuche) Oil as a Pharm‐Food to Prevent Ocular Hypertension and Fibrotic Events in the Retina of Hypertensive Mice

Á Santana‐Garrido, C Reyes‐Goya… - Molecular Nutrition & …, 2024 - Wiley Online Library
Scope Our laboratory has previously described the antioxidant and anti‐inflammatory
potential of a wild olive (acebuche, ACE) oil against hypertension‐associated vascular …

Retinoprotective effect of wild olive (Acebuche) oil-enriched diet against ocular oxidative stress induced by arterial hypertension

Á Santana-Garrido, C Reyes-Goya, MC Pérez-Camino… - Antioxidants, 2020 - mdpi.com
Oxidative stress plays an important role in the pathogenesis of ocular diseases, including
hypertensive eye diseases. The beneficial effects of olive oil on cardiovascular diseases …

Anti-angiogenic and antioxidant effects of axitinib in human retinal endothelial cells: implications in diabetic retinopathy

F Lazzara, F Conti, PK Sasmal, S Alikunju… - Frontiers in …, 2024 - frontiersin.org
Diabetic retinopathy is a secondary microvascular complication of diabetes mellitus. This
disease progresses from two stages, non-proliferative and proliferative diabetic retinopathy …

[HTML][HTML] Ophthalmic wild olive (ACEBUCHE) oil nanoemulsions exert oculoprotective effects against oxidative stress induced by arterial hypertension

Á Santana-Garrido, M Durán-Lobato, A Mate… - International Journal of …, 2024 - Elsevier
Oxidative stress plays a key role in several systemic and ocular diseases, including
hypertensive eye diseases. In this context, we previously showed that oral administration of …

Anti-Inflammatory action of dietary wild olive (Acebuche) oil in the retina of hypertensive mice

Á Santana-Garrido, C Reyes-Goya, S Milla-Navarro… - Foods, 2021 - mdpi.com
Inflammation plays a crucial role in the course of eye diseases, including many vascular
retinopathies. Although olive oil is known to have beneficial effects against inflammatory …

Simvastatin attenuates silica-induced pulmonary inflammation and fibrosis in rats via the AMPK-NOX pathway

C Bo, F Liu, Z Zhang, Z Du, H Xiu, Z Zhang, M Li… - BMC Pulmonary …, 2024 - Springer
Abstract Background Simvastatin (Sim), a hydroxy-methylglutaryl coenzyme A (HMG-CoA)
reductase inhibitor, has been widely used in prevention and treatment of cardiovascular …

[HTML][HTML] Presumed bilateral diffuse uveal melanocytic proliferation–A case report and review of literature

S Parakh, S Maheshwari, S Das, V Kumar… - American Journal of …, 2022 - Elsevier
Purpose To describe a case of presumed bilateral diffuse uveal melanocytic proliferation
(BDUMP) associated with renal cell carcinoma (RCC) and provide an updated review of …

Sunitinib displays pulmonary fibrosis in experimental rats: Role of IL-17A dependent pathway

ME Asker, AA Abdelmeged, MA Shaheen… - International …, 2023 - Elsevier
Sunitinib (SUN) is an FDA approved first line drug for management of metastatic renal
cancers and advanced cancerous states of gastrointestinal tract, however, side effects …

Insulin resistance and pellino-1 mediated decrease in the activities of vasodilator signaling contributes to sunitinib-induced hypertension

Y Liu, LL Tang, C Liang, MM Wu… - Frontiers in …, 2021 - frontiersin.org
Antiangiogenic tyrosine kinases inhibitors induce hypertension, which may increase the
incidents of cardiovascular complications and limit their use. However, the mechanisms by …