The rapid emergence of antifungal-resistant human-pathogenic fungi

SR Lockhart, A Chowdhary, JAW Gold - Nature Reviews Microbiology, 2023 - nature.com
During recent decades, the emergence of pathogenic fungi has posed an increasing public
health threat, particularly given the limited number of antifungal drugs available to treat …

One population, multiple lifestyles: commensalism and pathogenesis in the human mycobiome

DM Proctor, RA Drummond, MS Lionakis, JA Segre - Cell host & microbe, 2023 - cell.com
Candida auris and Candida albicans can result in invasive fungal diseases. And yet, these
species can stably and asymptomatically colonize human skin and gastrointestinal tracts. To …

[HTML][HTML] Update on the Pathogenesis, Virulence, and Treatment of Candida auris

RR Watkins, R Gowen, MS Lionakis… - Pathogens and …, 2022 - ncbi.nlm.nih.gov
Candida auris is an emerging, multidrug resistant fungal pathogen that causes considerable
morbidity and mortality. First identified in Japan in 2009, it has since been reported in more …

Role of Microbiota in the Skin Colonization of Candida auris

B Tharp, R Zheng, G Bryak, AP Litvintseva, MK Hayden… - Msphere, 2023 - Am Soc Microbiol
Candida auris is an emerging multidrug-resistant fungal pathogen that can cause life-
threatening infections in humans. Unlike other Candida species that colonize the gut, C …

Expert recommendations for prevention and management of Candida auris transmission

AM Aldejohann, M Wiese‐Posselt, P Gastmeier… - Mycoses, 2022 - Wiley Online Library
Candida auris was first described as a yeast pathogen in 2009. Since then, the species has
emerged worldwide. In contrast to most other Candida spp., C. auris frequently exhibits multi …

[HTML][HTML] Public health research priorities for fungal diseases: A multidisciplinary approach to save lives

DJ Smith, JAW Gold, K Benedict, K Wu, M Lyman… - Journal of Fungi, 2023 - mdpi.com
Fungal infections can cause severe disease and death and impose a substantial economic
burden on healthcare systems. Public health research requires a multidisciplinary approach …

[HTML][HTML] Finding Candida auris in public metagenomic repositories

JE Mario-Vasquez, UR Bagal, E Lowe, A Morgulis… - Plos one, 2024 - journals.plos.org
Candida auris is a newly emerged multidrug-resistant fungus capable of causing invasive
infections with high mortality. Despite intense efforts to understand how this pathogen …

Candida auris—macrophage cellular interactions and transcriptional response

P Miramón, AW Pountain, MC Lorenz - Infection and Immunity, 2023 - Am Soc Microbiol
The pathogenic yeast Candida auris represents a global threat of the utmost clinical
relevance. This emerging fungal species is remarkable in its resistance to commonly used …

Rapid Environmental Contamination With Candida auris and Multidrug-Resistant Bacterial Pathogens Near Colonized Patients

SE Sansom, GM Gussin, M Schoeny… - Clinical Infectious …, 2024 - academic.oup.com
Background Environmental contamination is suspected to play an important role in Candida
auris transmission. Understanding speed and risks of contamination after room disinfection …

[HTML][HTML] Modeling Candida auris skin colonization: Mice, swine, and humans

EF Eix, JE Nett - PLoS Pathogens, 2022 - journals.plos.org
The recently emergent fungal pathogen Candida auris frequently persists on skin of patients
and can cause invasive disease with mortality rates over 50%[1, 2]. It is the first fungal …