Mechanical forces may be generated within a cell due to tissue stiffness, cytoskeletal
reorganization, and the changes (even subtle) in the cell's physical surroundings. These …

Hyperhomocysteneinemia (HHcy) is common in the general population and is a risk factor
for atherosclerosis by mechanisms that are still elusive. A hypomethylated status of …

Accumulation of the homocysteine (Hcy) precursor S-adenosylhomocysteine (AdoHcy) may
cause cellular hypomethylation in the setting of hyperhomocysteinemia because of …

Tumors utilize multiple strategies to evade the recognition and eradication by the immune
system enabling outgrowth and resistance to cancer immunotherapy. There is increasing …

Elevated plasma total homocysteine (tHcy) is associated with increased risk of
cardiovascular disease, but the mechanisms underlying this association are not completely …

Protein methylation is a key post-translational modification that occurs on both histone and
non-histone proteins, as it regulates diverse cellular processes including gene expression …

The replacement of canonical histones with their variant forms is a key process by which all
aspects of genome function is regulated. The histone variant H2A. B is a testis-specific …

Neste projeto caracterizamos a interação da nucleoproteína viral (N) do Vírus Respiratório
Sincicial Humano (HRSV) com as proteínas PRMT5 e WDR77, que constituem o …

ABSTRACT OGAWA, JK Characterization of humam respiratory syncytial virus nucleoprotein
and methylosome interaction. 2016. 86 f. Disertation (Master in Microbiology)–Instituto de …

The interaction between folate and methylenetetrahydrofolate reductase (MTHFR) gene is
an example of a strong gene-nutrient interaction. MTHFR 677C→ T polymorphism may be …