The era of the ARG: An introduction to ancestral recombination graphs and their significance in empirical evolutionary genomics

AL Lewanski, MC Grundler, GS Bradburd - PLoS Genetics, 2024 - journals.plos.org
In the presence of recombination, the evolutionary relationships between a set of sampled
genomes cannot be described by a single genealogical tree. Instead, the genomes are …

A general and efficient representation of ancestral recombination graphs

Y Wong, A Ignatieva, J Koskela, G Gorjanc… - Genetics, 2024 - academic.oup.com
As a result of recombination, adjacent nucleotides can have different paths of genetic
inheritance and therefore the genealogical trees for a sample of DNA sequences vary along …

Biases in ARG-based inference of historical population size in populations experiencing selection

JI Marsh, P Johri - Molecular Biology and Evolution, 2024 - academic.oup.com
Inferring the demographic history of populations provides fundamental insights into species
dynamics and is essential for developing a null model to accurately study selective …

Inference and applications of ancestral recombination graphs

R Nielsen, AH Vaughn, Y Deng - Nature Reviews Genetics, 2024 - nature.com
Ancestral recombination graphs (ARGs) summarize the complex genealogical relationships
between individuals represented in a sample of DNA sequences. Their use is currently …

Divergence and gene flow history at two large chromosomal inversions underlying ecotype differentiation in the long‐snouted seahorse

L Meyer, P Barry, F Riquet, A Foote… - Molecular …, 2024 - Wiley Online Library
Chromosomal inversions can play an important role in divergence and reproductive
isolation by building and maintaining distinct allelic combinations between evolutionary …

[HTML][HTML] The era of the ARG: an empiricist's guide to ancestral recombination graphs

AL Lewanski, MC Grundler, GS Bradburd - ArXiv, 2023 - ncbi.nlm.nih.gov
In the presence of recombination, the evolutionary relationships between a set of sampled
genomes cannot be described by a single genealogical tree. Instead, the genomes are …

[HTML][HTML] Estimating evolutionary and demographic parameters via ARG-derived IBD

Z Huang, J Kelleher, Y Chan, DJ Balding - bioRxiv, 2024 - ncbi.nlm.nih.gov
Inference of demographic and evolutionary parameters from a sample of genome
sequences often proceeds by first inferring identical-by-descent (IBD) genome segments. By …