Contribution of advanced fluorescence nano microscopy towards revealing mitotic chromosome structure

SW Botchway, S Farooq, A Sajid, IK Robinson… - Chromosome …, 2021 - Springer
The organization of chromatin into higher-order structures and its condensation process
represent one of the key challenges in structural biology. This is important for elucidating …

Cryo-nanoscale chromosome imaging—future prospects

M Yusuf, S Farooq, I Robinson, EN Lalani - Biophysical Reviews, 2020 - Springer
The high-order structure of mitotic chromosomes remains to be fully elucidated. How
nucleosomes compact at various structural levels into a condensed mitotic chromosome is …

Toward quantitative super-resolution methods for cryo-CLEM.

LC Zanetti-Domingues, M Hirsch, L Wang… - Methods in cell …, 2024 - europepmc.org
Cryogenic ultrastructural imaging techniques such as cryo-electron tomography have
produced a revolution in how the structure of biological systems is investigated by enabling …