Strategies for safer liver surgery and partial liver transplantation

PA Clavien, H Petrowsky… - New England Journal …, 2007 - Mass Medical Soc
The liver possesses the unique ability to regenerate within a short period of time, a feature
that has led to the development of innovative strategies in liver surgery and transplantation …

Ischemia—reperfusion injury of the intestine and protective strategies against injury

IH Mallick, W Yang, MC Winslet… - Digestive diseases and …, 2004 - Springer
Ischemia—Reperfusion injury of the intestine is a significant problem in abdominal aortic
aneurysm surgery, small bowel transplantation, cardiopulmonary bypass, strangulated …

An ALOX12–12-HETE–GPR31 signaling axis is a key mediator of hepatic ischemia–reperfusion injury

XJ Zhang, XU Cheng, ZZ Yan, J Fang, X Wang… - Nature medicine, 2018 - nature.com
Hepatic ischemia–reperfusion (IR) injury is a common clinical issue lacking effective therapy
and validated pharmacological targets. Here, using integrative'omics' analysis, we identified …

Challenges to liver transplantation and strategies to improve outcomes

P Dutkowski, M Linecker, ML DeOliveira, B Müllhaupt… - Gastroenterology, 2015 - Elsevier
Liver transplantation (LT) is a highly successful treatment for many patients with
nonmalignant and malignant liver diseases. However, there is a worldwide shortage of …

Current strategies to minimize hepatic ischemia–reperfusion injury by targeting reactive oxygen species

H Jaeschke, BL Woolbright - Transplantation reviews, 2012 - Elsevier
Ischemia–reperfusion is a major component of injury in vascular occlusion both during liver
surgery and during liver transplantation. The pathophysiology of hepatic ischemia …

[HTML][HTML] Autophagy in liver diseases

PE Rautou, A Mansouri, D Lebrec, F Durand… - Journal of …, 2010 - Elsevier
Autophagy, or cellular self-digestion, is a cellular pathway crucial for development,
differentiation, survival, and homeostasis. Its implication in human diseases has been …

Liver failure after partial hepatic resection: definition, pathophysiology, risk factors and treatment

MAJ Van Den Broek, SWM Olde Damink… - Liver …, 2008 - Wiley Online Library
Liver failure is a dreaded and often fatal complication that sometimes follows a partial
hepatic resection. This article reviews the definition, incidence, pathogenesis, risk factors …

[HTML][HTML] Studies of jet quenching using isolated-photon+ jet correlations in PbPb and pp collisions at sNN= 2.76 TeV

S Chatrchyan, V Khachatryan, AM Sirunyan… - Physics Letters B, 2013 - Elsevier
Results from the first study of isolated-photon+ jet correlations in relativistic heavy ion
collisions are reported. The analysis uses data from PbPb collisions at a centre-of-mass …

Factors in the pathophysiology of the liver ischemia-reperfusion injury

EE Montalvo-Jave, T Escalante-Tattersfield… - Journal of Surgical …, 2008 - Elsevier
Hepatic ischemia-reperfusion injury is commonplace in liver surgery, particularly in hepatic
transplantation, hepatic resection, and trauma. The signaling events contributing to local …

[HTML][HTML] Current and future treatments for hepatocellular carcinoma

A Schlachterman, WW Craft Jr… - World journal of …, 2015 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) represents a unique challenge for physicians and patients.
There is no definitively curative treatment. Rather, many treatment and management …