Simple Summary The Hedgehog/GLI (Hh/GLI) pathway plays a major role during
development and it is commonly dysregulated in many diseases, including cancer. This …

Arterial dissections, which involve an abrupt tear in the wall of a major artery resulting in the
intramural accumulation of blood, are a family of catastrophic disorders causing major …

Lung-function impairment underlies chronic obstructive pulmonary disease (COPD) and
predicts mortality. In the largest multi-ancestry genome-wide association meta-analysis of …

Cigarette smoke (CS) leads to increased oxidative stress, inflammation, and exaggerated
senescence, which are involved in the pathogenesis of chronic obstructive pulmonary …

Plant-derived exosome-like nanoparticles (ELNs) have been proposed as a novel
therapeutic tool for preventing human diseases. However, the number of well-verified plant …

The hippocampus is critical for memory and cognition and neuropsychiatric disorders, and
its subfields differ in architecture and function. Genome-wide association studies on …

Background The identification of markers and genes for growth traits may not only benefit for
marker assist selection/genomic selection but also provide important information for …

An incomplete understanding of the molecular mechanisms behind impairment of lung
pathobiology by COVID-19 complicates its clinical management. In this study, we analyzed …

Th17 cells are key drivers of autoimmune disease. However, the signaling pathways
regulating Th17 polarization are poorly understood. Hedgehog signaling regulates cell fate …

During human spermatogenesis, germ cells undergo dynamic changes in chromatin
organization/re-packaging and in transcriptomes. In order to better understand the …