Molecular genetic manipulation of micro‐organisms requires the development of plasmid‐
mediated transformation systems that include:(i) infusion of exogenous DNA into recipient …

Filamentous fungi are important in medicine, industry, agriculture, and basic biological
research. For example, some fungal species are pathogenic to humans, whereas others …

An efficient transformation system for the cellulolytic filamentous fungus Trichoderma reesei
has been developed. Transformation was obtained with plasmid carrying the dominant …

A new, heterologous, dominant marker for selection of Aspergillus transformants is
described. This marker is based on the Escherichia coli hygromycin B (HmB) …

We constructed a chimeric plasmid carrying a complete copy of the trifunctional trpC gene
from the Ascomycete fungus Aspergillus nidulans. This plasmid, designated pHY201 …

DNA-mediated genetic transformation of Aspergillus nidulans has been achieved by
incubating protoplasts from a strain of A. nidulans carrying a deletion in the acetamidase …

ABSTRACT Xyr1 (xylanase regulator 1) of the ascomycete Hypocrea jecorina (anamorph
Trichoderma reesei) was recently demonstrated to play an essential role in the …

The complete nucleotide sequence derived from a genomic clone and two cDNA clones of
the creA gene of Aspergillus nidulans is presented. The gene contains no introns. The …

Aspergillus niger grows poorly on acetamide as a nitrogen or carbon source and lacks
sequences detectably homologous to the amdS gene encoding the acetamidase of …

The cre1 genes of the filamentous fungi Trichoderma reesei and T. harzianum were isolated
and characterized. The deduced CREI proteins are 46% identical to the product of the …