Centrosome amplification is a hallmark of cancer. However, despite significant progress in
recent years, we are still far from understanding how centrosome amplification affects …

Centrosomes are microtubule-organizing centres of animal cells. They influence the
morphology of the microtubule cytoskeleton, function as the base for the primary cilium and …

Centrioles are barrel-shaped structures that are essential for the formation of centrosomes,
cilia, and flagella. Here we review recent advances in our understanding of the function and …

Centrioles are essential for the formation of cilia and flagella. They also form the core of the
centrosome, which organizes microtubule arrays important for cell shape, polarity, motility …

Formation of one procentriole next to each pre-existing centriole is essential for centrosome
duplication, robust bipolar spindle assembly and maintenance of genome integrity …

The centriole, and the related basal body, is an ancient organelle characterized by a
universal 9-fold radial symmetry and is critical for generating cilia, flagella, and centrosomes …

The centrosome was discovered in the late 19th century when mitosis was first described.
Long recognized as a key organelle of the spindle pole, its core component, the centriole …

The centriole is an evolutionarily conserved macromolecular structure that is crucial for the
formation of flagella, cilia and centrosomes. The ultrastructure of the centriole was first …

Over a century ago, centrosome aberrations were postulated to cause cancer by promoting
genome instability. The mechanisms governing centrosome assembly and function are …

Centrioles are cylindrical, ninefold symmetrical structures with peripheral triplet microtubules
strictly required to template cilia and flagella. The highly conserved protein SAS-6 …