The increased application of transcriptome-wide profiling approaches has led to an
explosion in the number of documented long non-coding RNAs (lncRNAs). While these new …

Long non-coding RNAs (lncRNAs) are emerging as new players in the cancer paradigm
demonstrating potential roles in both oncogenic and tumor suppressive pathways. These …

The flowering plant Arabidopsis thaliana is a dicot model organism for research in many
aspects of plant biology. A comprehensive annotation of its genome paves the way for …

Long noncoding RNAs (lncRNAs) have gained widespread attention in recent years as a
potentially new and crucial layer of biological regulation. lncRNAs of all kinds have been …

Understanding the extent of genomic transcription and its functional relevance is a central
goal in genomics research. However, detailed genome-wide investigations of transcriptome …

Aims Circular RNA (circRNA) is a newly validated class of single-stranded RNA,
ubiquitously expressed in mammalian tissues and possessing key functions including acting …

Cancers have a high mortality rate due to lack of suitable specific early diagnosis tumor
biomarkers. Emerging evidence is accumulating that lncRNAs (long noncoding RNAs) are …

The conventional view of gene regulation in biology has centered around protein-coding
genes via the central dogma of DNA→ mRNA→ protein. The discovery of thousands of long …

Lung cancer is the leading cause of cancer death worldwide, accounting for more deaths
than breast, prostate and colon cancer combined. While treatment decisions are determined …

Diabetic nephropathy (DN) as the primary cause of end-stage kidney disease is a common
complication of diabetes. Recent researches have shown the activation of nuclear factor …