Sex differences in cocaine sensitization vary by mouse strain
AD Chapp, CA Nwakama, MJ Thomas, RL Meisel… - …, 2023 - karger.com
Introduction: Preclinical literature, frequently utilizing rats, suggests females display a more
rapid advancement of substance abuse and a greater risk of relapse following drug …
rapid advancement of substance abuse and a greater risk of relapse following drug …
Extreme phenotypic diversity in operant response to intravenous cocaine or saline infusion in the hybrid mouse diversity panel
Cocaine self‐administration is a complexly determined trait, with a substantial proportion of
individual differences being determined by genetic variation. However, the relevant genetic …
individual differences being determined by genetic variation. However, the relevant genetic …
[HTML][HTML] Behavioral phenotypes revealed during reversal learning are linked with novel genetic loci in diversity outbred mice
Impulsive behavior and impulsivity are heritable phenotypes that are strongly associated
with risk for substance use disorders. Identifying the neurogenetic mechanisms that …
with risk for substance use disorders. Identifying the neurogenetic mechanisms that …
Do gene expression findings from mouse models of cocaine use recapitulate human cocaine use disorder in reward circuitry?
SB Huggett, JA Bubier, EJ Chesler… - Genes, Brain and …, 2021 - Wiley Online Library
Animal models of drug use have investigated possible mechanisms governing human
substance use traits for over 100 years. Most cross‐species research on drug use/addiction …
substance use traits for over 100 years. Most cross‐species research on drug use/addiction …
The collaborative cross strains and their founders vary widely in cocaine-induced behavioral sensitization
SA Schoenrock, L Gagnon, A Olson… - Frontiers in Behavioral …, 2022 - frontiersin.org
Cocaine use and overdose deaths attributed to cocaine have increased significantly in the
United States in the last 10 years. Despite the prevalence of cocaine use disorder (CUD) …
United States in the last 10 years. Despite the prevalence of cocaine use disorder (CUD) …
Reversal Learning Phenotypes are Linked with Novel Genetic Loci in Diversity Outbred Mice
Impulsive behavior and impulsivity are heritable phenotypes that are strongly associated
with risk for substance use disorders in human subjects. Consequently, identifying the …
with risk for substance use disorders in human subjects. Consequently, identifying the …