Activity-based NIR fluorescent probes based on the versatile hemicyanine scaffold: design strategy, biomedical applications, and outlook

H Li, H Kim, F Xu, J Han, Q Yao, J Wang, K Pu… - Chemical Society …, 2022 - pubs.rsc.org
The discovery of a near-infrared (NIR, 650–900 nm) fluorescent chromophore hemicyanine
dye with high structural tailorability is of great significance in the field of detection …

Research progress on the SERPINE1 protein and chronic inflammatory diseases of the upper respiratory tract: a literature review

T Chen, M Zhou, M Lin, S Liang, Y Yan… - … Archives of Allergy and …, 2021 - karger.com
SERPINE1 protein is one important member of the serine proteinase inhibitor E superfamily
that plays a crucial role in the fibrinolytic system. It has been identified which is related to …

Candidate prognostic markers in breast cancer: focus on extracellular proteases and their inhibitors

DM Roy, LA Walsh - Breast Cancer: Targets and Therapy, 2014 - Taylor & Francis
The extracellular matrix (ECM) is the complex network of proteins that surrounds cells in
multicellular organisms. Due to its diverse nature and composition, the ECM has a …

Multifunctional roles of urokinase plasminogen activator (uPA) in cancer stemness and chemoresistance of pancreatic cancer

S Asuthkar, V Stepanova, T Lebedeva… - Molecular biology of …, 2013 - Am Soc Cell Biol
Pancreatic ductal adenocarcinoma (PDAC) is almost always lethal. One of the underlying
reasons for this lethality is believed to be the presence of cancer stem cells (CSC), which …

GPI transamidase and GPI anchored proteins: oncogenes and biomarkers for cancer

DG Gamage, TL Hendrickson - Critical reviews in biochemistry and …, 2013 - Taylor & Francis
Cancer is second only to heart disease as a cause of death in the US, with a further negative
economic impact on society. Over the past decade, details have emerged which suggest that …

Molecular targets in hepatocarcinogenesis and implications for therapy

MY Wu, GT Yiang, PW Cheng, PY Chu… - Journal of clinical medicine, 2018 - mdpi.com
Hepatocarcinogenesis comprises of multiple, complex steps that occur after liver injury and
usually involve several pathways, including telomere dysfunction, cell cycle, WNT/β-catenin …

Proanthocyanidin in red rice inhibits MDA-MB-231 breast cancer cell invasion via the expression control of invasive proteins

K Pintha, S Yodkeeree, P Limtrakul - Biological and Pharmaceutical …, 2015 - jstage.jst.go.jp
Proanthocyanidin is one of the main active compounds found in red jasmine rice. We
previously reported that red rice extract could reduce cancer cell invasion. However, the …

Epithelial-mesenchymal transition induced PAI-1 is associated with prognosis of triple-negative breast cancer patients

J Xu, W Zhang, L Tang, W Chen, X Guan - Gene, 2018 - Elsevier
Epithelial-mesenchymal transition (EMT) is a key developmental program in which epithelial
cells lose polarity and become mesenchymal cells, and that is often activated during cancer …

The value of MMP-9 for breast and non-small cell lung cancer patients' survival

D Schveigert, S Cicenas, S Bruzas… - Advances in medical …, 2013 - Elsevier
ABSTRACT Purpose Matrix metalloproteinases (MMPs) are implicated in cancer cells
invasion and metastasis processes and have been investigated as potential cancer …

Potential therapeutic role for pigment epithelium-derived factor in post-menopausal breast cancer bone metastasis

N Brook, A Dharmarajan, A Chan… - Journal of Pharmacy …, 2023 - academic.oup.com
Objectives This review discusses key oestrogens associated with the circulating pre-and
post-menopausal milieu and how they may impact intratumoral oestrogen levels and breast …