M Fudim, S Sayeed, H Xu, RA Matsouaka… - Circulation: Heart …, 2020 - Am Heart Assoc
Background: In PIONEER-HF (Comparison of Sacubitril/Valsartan Versus Enalapril on Effect on NT-pro BNP in Patients Stabilized From an Acute Heart Failure Episode), the in-hospital …
Background Sacubitril/Valsartan has been highly efficacious in randomized trials of heart failure with reduced ejection fraction (HFrEF). However, the effectiveness of …
Background Prior study has demonstrated that transitioning patients in acutely decompensated heart failure with a low cardiac output directly from intravenous (iv) …
The benefits of angiotensin receptor-neprilysin inhibitor (ARNI) in patients with heart failure with reduced ejection fraction (HFrEF) are well established (1). The majority of patients with …
Neprilysin due to its peptidase activity is involved in several physiological and pathological processes. Recently our group has reported the association of neprilysin with angiotensin …