Abstract von Hippel–Lindau (VHL) disease is an inheritable condition with an incidence of 1
in 36 000 live births. Individuals with VHL develop benign and malignant tumors including …

Background Posterior cranial fossa (PCF) hemangioblastomas are benign, highly
vascularized, and well-differentiated tumors with well-described histopathologic features …

OBJECT The aim of this study was to enhance the planning and use of microsurgical
resection techniques for intrinsic brainstem lesions by better defining anatomical safe entry …

Object The tumors most frequently associated with von Hippel-Lindau (VHL) disease are
hemangioblastomas. While they are associated with significant neurological impairment and …

Importance von Hippel–Lindau (VHL) disease–associated central nervous system (CNS)
lesions include hemangioblastomas and endolymphatic sac tumors (ELSTs), which are …

Introduction While preoperative embolization is often reserved for large and highly vascular
tumors in order to minimize blood loss, its safety and efficacy in the treatment of …

von Hippel-Lindau (VHL) disease is an autosomal-dominant familial cancer syndrome
associated with mutations of the VHL tumor suppressor gene (3p25-26). Its estimated …

Patients with von Hippel–Lindau disease (VHL) often harbor significant disease burden
within the CNS, specifically craniospinal-axis hemangioblastomas and endolymphatic sac …

OBJECT Peritumoral cysts are frequently associated with CNS hemangioblastomas and
often underlie neurological morbidity and mortality. To determine their natural history and …

Hemangioblastomas (HBs) are highly vascularized, slow-growing, rare benigntumors (WHO
grade I). They account for about 2% of intracranialneoplasms; however, they are the most …