Age-related diseases, such as Parkinson's disease, Alzheimer's disease, cardiovascular
diseases, cancers, and age-related macular disease, have become increasingly prominent …

In daylight, demand for visual chromophore (11-cis-retinal) exceeds supply by the classical
visual cycle. This shortfall is compensated, in part, by the retinal G-protein-coupled receptor …

Significance: Dihydrolipoamide dehydrogenase (DLDH) is a flavin-dependent disulfide
oxidoreductase. The active form of DLDH is a stable homodimer, and its deficiencies have …

Excessive light exposure can damage photoreceptors and lead to blindness. Oxidative
stress serves a key role in photo-induced retinal damage. Free radical scavengers have …

Rationale: Müller cells play an essential role in maintaining the health of retinal
photoreceptors. Dysfunction of stressed Müller cells often results in photoreceptor …

Fetal growth restriction (FGR) occurs when the fetus does not reach its genetically
programmed intrauterine potential for growth and affects~ 5–10% of pregnancies. This …

Müller glial cells (MC) support various metabolic functions of the retinal neurons, and
maintain the homeostasis. Oxidative stress is intensified with aging, and in human retina …

Purpose: Retinal neovascularization poses heightened risks of vision loss and blindness.
Despite its clinical significance, the molecular mechanisms underlying the pathogenesis of …

A series of novel nitric oxide (NO)-releasing 5, 8-quinolinedione/furoxan hybrids (8a-h and
9a-h) were designed and synthesized through coupling different alkanolamine substituted …

Abstract Introduction Granulosa cells (GCs) is essential for maintaining follicular
development. Follicle-stimulating Hormone (FSH) has been demonstrated to effectively …