[HTML][HTML] Cyclodextrins and derivatives in drug delivery: New developments, relevant clinical trials, and advanced products

G Kali, S Haddadzadegan, A Bernkop-Schnürch - Carbohydrate Polymers, 2024 - Elsevier
Cyclodextrins (CD) and derivatives are functional excipients that can improve the
bioavailability of numerous drugs. Because of their drug solubility improving properties they …

[HTML][HTML] Redox dual-stimuli responsive drug delivery systems for improving tumor-targeting ability and reducing adverse side effects

R Li, F Peng, J Cai, D Yang, P Zhang - Asian journal of pharmaceutical …, 2020 - Elsevier
Cancer is a big challenge that has plagued the human beings for ages and one of the most
effective treatments is chemotherapy. However, the low tumor-targeting ability limits the wide …

Development of a light-controlled nanoplatform for direct nuclear delivery of molecular and nanoscale materials

YX Zhu, HR Jia, GY Pan, NW Ulrich… - Journal of the …, 2018 - ACS Publications
Research on nanomedicines has rapidly progressed in the past few years. However, due to
the limited size of nuclear pores (9–12 nm), the nuclear membrane remains a difficult barrier …

Visible Light-Guided Gene Delivery with Nonviral Supramolecular Block Copolymer Vectors

W Yasen, B Li, A Aini, Z Li, Y Su, L Zhou… - … Applied Materials & …, 2023 - ACS Publications
To achieve efficient gene delivery in vitro or in vivo, nonviral vectors should have excellent
biostability across cellular and tissue barriers and also smart stimuli responsiveness toward …

Polyrotaxane‐Based Functional Materials Enabled by Molecular Mobility and Conformational Transition

Q Cui, X Zhang - Chinese Journal of Chemistry, 2023 - Wiley Online Library
Comprehensive Summary Slide‐ring structured polyrotaxanes with high molecular mobility
and reversible conformational transition ability can achieve high performance and …

Stimuli-regulated smart polymeric systems for gene therapy

AP Mathew, KH Cho, S Uthaman, CS Cho, IK Park - Polymers, 2017 - mdpi.com
The physiological condition of the human body is a composite of different environments,
each with its own parameters that may differ under normal, as well as diseased conditions …

Virus‐inspired nanogenes free from man‐made materials for host‐specific transfection and bio‐aided MR imaging

JY Zhu, MK Zhang, XG Ding, WX Qiu, WY Yu… - Advanced …, 2018 - Wiley Online Library
Many viruses have a lipid envelope derived from the host cell membrane that contributes
much to the host specificity and the cellular invasion. This study puts forward a virus …

High homology-directed repair using mitosis phase and nucleus localizing signal

JP Han, YJ Chang, DW Song, BS Choi, OJ Koo… - International journal of …, 2020 - mdpi.com
In homology-directed repair, mediated knock-in single-stranded oligodeoxynucleotides
(ssODNs) can be used as a homologous template and present high efficiency, but there is …

Porphyrin-terminated nanoscale fluorescent polyrotaxane as a biodegradable drug carrier for anticancer research

Y Zhang, S Jia, J Yuan, P Zhu, Y Gan, G Fan… - …, 2020 - iopscience.iop.org
Drug delivery carriers hold tremendous promise for improving cancer treatment, and
polyrotaxane (PR) has shown excellent drug-carrying properties. However, there have been …

Cationic cross-linked polymers containing labile disulfide and boronic ester linkages for effective triple responsive DNA release

S Sahoo, S Maiti, P Poddar, D Dhara - Colloids and Surfaces B …, 2020 - Elsevier
Disruption of DNA carriers triggered by intracellular bio-stimulants has been broadly
considered as most convenient strategy for efficient DNA delivery. In this direction, we have …