Atherosclerotic cardiovascular (CV) disease (ASCVD) incidence and mortality rates are
declining in many countries in Europe, but it is still a major cause of morbidity and mortality …

Cardiovascular diseases (CVDs) are the leading causes of morbidity and mortality in
individuals with type 2 diabetes mellitus (T2DM). Secular changes in CVD outcomes have …

ABSTRACT Abbreviations: A1C= hemoglobin A1C; AACE= American Association of Clinical
Endocrinologists; ABCD= adiposity-based chronic disease; ACCORD= Action to Control …

Background Patients with diabetes are at higher risk for death and cardiovascular outcomes
than the general population. We investigated whether the excess risk of death and …

Among 20 leading global risk factors for years of life lost in 2040, reference forecasts point to
three metabolic risks—high blood pressure, high BMI, and high fasting plasma glucose—as …

The treatment of lipid disorders begins with lifestyle therapy to improve nutrition, physical
activity, weight, and other factors that affect lipids. Secondary causes of lipid disorders …

Aims To develop and validate a recalibrated prediction model (SCORE2-Diabetes) to
estimate the 10-year risk of cardiovascular disease (CVD) in individuals with type 2 diabetes …

Background Chronic inflammation is believed to be a major mechanism underlying the
pathophysiology of type 2 diabetes. Periodontitis is a cause of systemic inflammation. We …

ABSTRACT Abbreviations: A1C= hemoglobin A1C; AACE= American Association of Clinical
Endocrinologists; ACCORD= Action to Control Cardiovascular Risk in Diabetes; ACCORD …

Background: In the EMPA-REG OUTCOME trial (BI 10773 [Empagliflozin] Cardiovascular
Outcome Event Trial in Type 2 Diabetes Mellitus Patients) in patients with type 2 diabetes …