p62/SQSTM 1 is a multifunctional signaling hub and autophagy adaptor with many binding
partners, which allow it to activate mTORC 1‐dependent nutrient sensing, NF‐κB‐mediated …

Gankyrin (also known as PSMD10 or p28GANK), engages in diverse biological processes,
including cellular growth, proliferation and invasion. Several studies have demonstrated that …

The poor prognosis of clear-cell renal cell carcinoma (ccRCC) patients is due to progression
and targeted drug resistance, but the underlying molecular mechanisms need further …

Colorectal cancer is one of the most serious tumors and berberine can inhibit the recurrence
and transformation of colorectal adenoma into colorectal cancer. However, the direct binding …

Rab1A overexpression has been observed in several cancer types, however, its significance
and the underlying mechanisms in non-small cell lung cancer (NSCLC) remain largely …

Sexual minority (ie, non-heterosexual) individuals experience poorer mental and physical
health, accounted for in part by the additional burden of sexual minority stress occurring from …

Rab1A expression is associated with malignant phenotypes in several human tumors;
however, the role of Rab1A in lung cancer is still unclear. In this study, we attempted to …

Our previous research showed that Gankyrin was overexpressed in NSCLC and significantly
associated with clinicopathologic features and poor prognosis. In this study, we will explore …

Gankyrin (also called PSMD10, p28, or p28 GANK) is a crucial oncoprotein that is
upregulated in various cancers and assumed to play pivotal roles in the initiation and …

Background In the clinic, how to stratify renal cell carcinoma (RCC) patients with different
risks and to accurately predict their prognostic outcome remains a crucial issue. In this study …