[HTML][HTML] Idebenone: When an antioxidant is not an antioxidant

N Gueven, P Ravishankar, R Eri, E Rybalka - Redox biology, 2021 - Elsevier
Idebenone is a well described drug that was initially developed against dementia. The
current literature widely portrays this molecule as a potent antioxidant and CoQ 10 …

[PDF][PDF] Nitrate-nitrite-nitric oxide pathway: implications for anesthesiology and intensive care

E Weitzberg, M Hezel, JO Lundberg… - …, 2010 - jvsmedicscorner.com
The gaseous radical nitric oxide is involved in numerous physiologic and pathophysiological
events important in anesthesiology and intensive care. Nitric oxide is endogenously …

Idebenone alleviates neuroinflammation and modulates microglial polarization in LPS-stimulated BV2 cells and MPTP-induced Parkinson's disease mice

A Yan, Z Liu, L Song, X Wang, Y Zhang… - Frontiers in cellular …, 2019 - frontiersin.org
Background: Idebenone is an antioxidant and a coenzyme Q10 analog that has been used
to treat neurodegeneration disease. Some studies show idebenone exerts anti-inflammatory …

In vitro digestibility of proteins, peptidomic analysis and antioxidant ability of sodium-reduced pork sausage with partial substitution of NaCl by KCl

L Zou, X Yu, Y Zhou, C Chen, G Xiao - Meat Science, 2023 - Elsevier
High salt (NaCl) consumption can impact on human health, and KCl is the most widely used
replacement salt in meat products. This study investigated the effects of 0% NaCl (NS), 3 …

Quercetin and idebenone ameliorate oxidative stress, inflammation, DNA damage, and apoptosis induced by titanium dioxide nanoparticles in rat liver

LM Fadda, H Hagar, AM Mohamed… - Dose-Response, 2018 - journals.sagepub.com
Titanium dioxide nanoparticles (TiO2-NPs) are extensively used in a wide range of
applications; however, many reports have investigated their nanotoxicological effect at the …

精氨酸抗氧化作用机制.

梁明才, 杨林 - Chinese Journal of Bioinformatics, 2020 - search.ebscohost.com
精氨酸是一种功能性氨基酸, 在机体生理功能, 新陈代谢和营养等方面发挥着重要作用.
精氨酸具有抗氧化能力. 目前的体外研究表明精氨酸具有较强的清除DPPH 自由基, ABTS …

Idebenone prevents oxidative stress, cell death and senescence of retinal pigment epithelium cells by stabilizing BAX/Bcl-2 ratio

N Arend, C Wertheimer, P Laubichler, A Wolf… - …, 2015 - karger.com
Purpose: Age-related macular degeneration (AMD) is one of the leading causes of
blindness. Degeneration of the retinal pigment epithelium (RPE) is pathognomonic for the …

Potential impact of quercetin and idebenone against immuno-inflammatory and oxidative renal damage induced in rats by titanium dioxide nanoparticles toxicity

NM Al-Rasheed, AM Mohamed, NAA Baky… - Journal of oleo …, 2013 - jstage.jst.go.jp
The aim of this study was to investigate the toxic impacts of titanium dioxide nanoparticles
(TiO 2-NPs) on rat kidneys and the possible prophylactic role of either quercetin or …

Protection of dystrophic muscle cells using Idebenone correlates with the interplay between calcium, oxidative stress and inflammation

AH Valduga, DS Mizobuti, FSR Moraes… - International journal …, 2023 - Wiley Online Library
There is strong cross‐talk between abnormal intracellular calcium concentration, high levels
of reactive oxygen species (ROS) and an exacerbated inflammatory process in the …

The protective effects of Cyperus rotundus on behavior and cognitive function in a rat model of hypoxia injury

D Jebasingh, D Devavaram Jackson… - Pharmaceutical …, 2014 - Taylor & Francis
Context: Hypoxia injury (HI) with its long-term neurological complications is one of the
leading causes of morbidity and mortality in the world. Currently, the treatment regimens for …