Dendritic cells are at the center of immune responses. They are defined by their ability to
sense the environment, take up and process antigen, migrate to secondary lymphoid …

To monitor the health of cells, the immune system tasks antigen-presenting cells with
gathering antigens from other cells and bringing them to CD8 T cells in the form of peptides …

Tumours have developed strategies to interfere with most steps required for anti-tumour
immune responses. Although many populations contribute to anti-tumour responses, tumour …

Cross-presentation is one of the main features of dendritic cells (DCs), which is critically
important for the development of spontaneous and therapy-inducible antitumor immune …

Oncogene activation in tumor cells induces broad and complex cellular changes that
contribute significantly to disease initiation and progression. In melanoma, oncogenic …

Dendritic cells (DCs) are currently considered to be of utmost importance for orchestrating
appropriate immune responses in vivo, and play critical roles in maintaining the distinction …

Cancer and the immune system are intimately related. Much of the bulk of tumors is
comprised of stromal leukocytes with immune functions, which serve to both promote and …

Immune responses are initiated and primed by dendritic cells (DCs) that cross-present
exogenous antigen. The chaperone CD74 (invariant chain) is thought to promote DC …

Cross-presentation allows antigen-presenting cells to present exogenous antigens to CD8+
T cells, playing an essential role in controlling infections and tumor development. IFN-α …

Bioorthogonal deprotections are readily used to control biological function in a cell-specific
manner. To further improve the spatial resolution of these reactions, we here present a …