Organic anion-transporting polypeptides or OATPs are central transporters in the disposition
of drugs and other xenobiotics. In addition, they mediate transport of a wide variety of …

Organic anion transporting polypeptides (OATPs) are membrane proteins that mediate the
uptake of a wide range of substrates across the plasma membrane of various cells and …

Traumatic brain injury (TBI) is responsible for various neuronal and cognitive deficits as well
as psychosocial dysfunction. Characterized by damage inducing neuroinflammation, this …

Organic anion-transporting polypeptide (OATP) 1A2 is expressed on the apical sides of
intestinal and renal epithelial cells and considered to be involved in the intestinal absorption …

Organic anion and cation transporting proteins (OATs, OATPs, and OCTs), as well as the
Multidrug and Toxin Extrusion (MATE) transporters of the Solute Carrier (SLC) family are …

Organic anion transporting polypeptides (OATPs) are membrane proteins that mediate the
uptake of a wide range of substrates across the plasma membrane of various cells and …

Key points The placenta removes waste products, drugs and environmental toxins from the
fetal circulation and two of the transport proteins responsible for this are OAT4 and …

Differential equations are used to describe time-dependent changes in enzyme kinetics and
pharmacokinetics. Analytical and numerical methods can be used to solve differential …

Undesirable substances in feed can transfer into foods of animal origin after ingestion by
livestock animals. These contaminants in food may threaten consumer health. Commonly …

Drug transporters are important determinants in drug disposition, efficacy, and toxicity. They
influence the pharmacokinetics and pharmacodynamics of drugs. Several clinically …