Highlights•First malaria vaccine RTS, S induces anti-sporozoite antibodies to protect
children.•Whole-sporozoite vaccines induce T cells and antibodies and confer field …

Infections with Plasmodium falciparum and Plasmodium vivax cause over 600,000 deaths
each year, concentrated in Africa and in young children, but much of the world's population …

Malaria killed over 600,000 people in 2022, a death toll that has not improved since 2015.
Additionally, parasites and mosquitoes resistant to existing interventions are spreading …

Aim The review summarizes the recent empirical evidence on the efficacy, safety, and
community perception of malaria vaccines in Africa. Methods Academic Search Complete …

Malaria remains one of the biggest health problems in the world. While significant reductions
in malaria morbidity and mortality had been achieved from 2000 to 2015, the favorable trend …

Background Malaria and schistosomiasis persist as major public health challenge in sub-
Saharan Africa. These infections have independently and also in polyparasitic infection …

Two malaria transmission-blocking vaccine (TBV) candidates, R0. 6C and ProC6C, have
completed preclinical development including the selection of adjuvants, Alhydrogel® with or …

Despite the many efforts of researchers around the world, there is currently no effective
vaccine for malaria. Numerous studies have been developed to find vaccine antigens that …

Information on the dynamics and decline/persistence of antibody titres is important in
vaccine development. A recent vaccine trial in malaria-exposed, healthy African adults and …

Malaria infections in school-age children further make it difficult to control the disease's
spread. Moreover, the genetic diversity of glutamate-rich protein, potentially a candidate for …