[HTML][HTML] Insights into SARS-CoV-2 genome, structure, evolution, pathogenesis and therapies: Structural genomics approach

AAT Naqvi, K Fatima, T Mohammad, U Fatima… - … et Biophysica Acta (BBA …, 2020 - Elsevier
The sudden emergence of severe respiratory disease, caused by a novel severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), has recently become a public health …

Review of Hepatitis E Virus in Rats: Evident Risk of Species Orthohepevirus C to Human Zoonotic Infection and Disease

G Reuter, Á Boros, P Pankovics - Viruses, 2020 - mdpi.com
Hepatitis E virus (HEV)(family Hepeviridae) is one of the most common human pathogens,
causing acute hepatitis and an increasingly recognized etiological agent in chronic hepatitis …

Viral macro domains reverse protein ADP-ribosylation

C Li, Y Debing, G Jankevicius, J Neyts, I Ahel… - Journal of …, 2016 - Am Soc Microbiol
ABSTRACT ADP-ribosylation is a posttranslational protein modification in which ADP-ribose
is transferred from NAD+ to specific acceptors to regulate a wide variety of cellular …

Insights into a class of natural eugenol and its optimized derivatives as potential tobacco mosaic virus helicase inhibitors by structure-based virtual screening

Z Li, B Yang, Y Ding, J Meng, J Hu, X Zhou, L Liu… - International Journal of …, 2023 - Elsevier
Plant diseases caused by malignant and refractory phytopathogenic viruses have
considerably restricted crop yields and quality. To date, drug design targeting functional …

Structural insights into RNA recognition by the Chikungunya virus nsP2 helicase

YS Law, A Utt, YB Tan, J Zheng… - Proceedings of the …, 2019 - National Acad Sciences
Chikungunya virus (CHIKV) is transmitted to humans through mosquitoes and causes
Chikungunya fever. Nonstructural protein 2 (nsP2) exhibits the protease and RNA helicase …

The cell biology of Tobacco mosaic virus replication and movement

C Liu, RS Nelson - Frontiers in plant science, 2013 - frontiersin.org
Successful systemic infection of a plant by Tobacco mosaic virus (TMV) requires three
processes that repeat over time: initial establishment and accumulation in invaded cells …

Functional cross-talk between distant domains of chikungunya virus non-structural protein 2 is decisive for its RNA-modulating activity

PK Das, A Merits, A Lulla - Journal of Biological Chemistry, 2014 - ASBMB
Chikungunya virus (CHIKV) non-structural protein 2 (nsP2) is a multifunctional protein that is
considered a master regulator of the viral life cycle and a main viral factor responsible for …

Arf-like GTPase Arl8: Moving from the periphery to the center of lysosomal biology

D Khatter, A Sindhwani, M Sharma - Cellular logistics, 2015 - Taylor & Francis
Lysosomes are dynamic organelles that not only mediate degradation of cellular substrates
but also play critical roles in processes such as cholesterol homeostasis, plasma membrane …

De novo modelling of HEV replication polyprotein: Five-domain breakdown and involvement of flexibility in functional regulation

S Fieulaine, T Tubiana, S Bressanelli - Virology, 2023 - Elsevier
Hepatitis E virus (HEV), a major cause of acute viral hepatitis, is a single-stranded, positive-
sense RNA virus. As such, it encodes a 1700-residue replication polyprotein pORF1 that …

Tobamoviruses: old and new threats to tomato cultivation

K Ishibashi, K Kubota, A Kano, M Ishikawa - Journal of General Plant …, 2023 - Springer
Mosaic diseases caused by tobamoviruses have posed significant threats to tomato
production. In this review, we overview studies of tomato mosaic diseases published over …