Protein Phosphatase 2 Regulatory Subunit B′ Delta (PPP2R5D)-related intellectual
disability (ID) and neurodevelopmental delay results from germline de novo mutations in the …

Here, we outline the mechanisms involved in the regulation of cell divisions during oocyte
maturation and early cleavages of the mouse embryo. Our interest is focused on the …

The elevated level of CCNB1 indicates more aggressive cancer and poor prognosis.
However, the factors that cause CCNB1 upregulation remain enigmatic. Herein, we identify …

Eukaryotic cell division requires the mitotic spindle, a microtubule (MT)-based structure
which accurately aligns and segregates duplicated chromosomes. The dynamics of spindle …

The mitotic checkpoint is a specialized signal transduction pathway that contributes to the
fidelity of chromosome segregation. The signaling of the checkpoint originates from …

Aim The mammalian ovary generates reactive oxygen species (ROS) on an extraordinary
scale; however, the role of ROS during meiotic cell cycle progression in follicular oocytes …

Asporin (ASPN), a member of small leucine-rich repeat proteoglycan (SLRP) family of
proteins, serves important roles in diverse biological responses and disease conditions. We …

Background: Although previous studies reported that 26S proteasome non-ATPase
regulatory subunit 2 (PSMD2) is involved in many human cancers. However, its clinical …

Abstract Hydrogen peroxide (H2O2) acts as a signaling molecule and modulates various
aspects of cell functions in a wide variety of cells including mammalian germ cells. We …

The microsporidian Nosema bombycis is an obligate intracellular pathogen of the silkworm
Bombyx mori, causing the epidemic disease Pebrine and extensive economic losses in …