Physiological roles of hydrogen sulfide in mammalian cells, tissues, and organs

G Cirino, C Szabo… - Physiological …, 2023 - journals.physiology.org
Over the last two decades, hydrogen sulfide (H2S) has emerged as an endogenous
regulator of a broad range of physiological functions. H2S belongs to the class of molecules …

International union of basic and clinical pharmacology. CII: pharmacological modulation of H2S levels: H2S donors and H2S biosynthesis inhibitors

C Szabo, A Papapetropoulos, EH Ohlstein - Pharmacological reviews, 2017 - Elsevier
Over the last decade, hydrogen sulfide (H 2 S) has emerged as an important endogenous
gasotransmitter in mammalian cells and tissues. Similar to the previously characterized …

Hydrogen sulfide: from a toxic molecule to a key molecule of cell life

A Aroca, C Gotor, DC Bassham, LC Romero - Antioxidants, 2020 - mdpi.com
Hydrogen sulfide (H2S) has always been considered toxic, but a huge number of articles
published more recently showed the beneficial biochemical properties of its endogenous …

H2S biosynthesis and catabolism: new insights from molecular studies

P Rose, PK Moore, YZ Zhu - Cellular and Molecular Life Sciences, 2017 - Springer
Hydrogen sulfide (H 2 S) has profound biological effects within living organisms and is now
increasingly being considered alongside other gaseous signalling molecules, such as nitric …

Plasticity of the maternal vasculature during pregnancy

G Osol, NL Ko, M Mandalà - Annual review of physiology, 2019 - annualreviews.org
Maternal cardiovascular changes during pregnancy include an expansion of plasma
volume, increased cardiac output, decreased peripheral resistance, and increased …

Uteroplacental circulation in normal pregnancy and preeclampsia: functional adaptation and maladaptation

X Hu, L Zhang - International journal of molecular sciences, 2021 - mdpi.com
Uteroplacental blood flow increases as pregnancy advances. Adequate supply of nutrients
and oxygen carried by uteroplacental blood flow is essential for the well-being of the mother …

Estrogen receptors and estrogen-induced uterine vasodilation in pregnancy

J Bai, QR Qi, Y Li, R Day, J Makhoul… - International journal of …, 2020 - mdpi.com
Normal pregnancy is associated with dramatic increases in uterine blood flow to facilitate the
bidirectional maternal–fetal exchanges of respiratory gases and to provide sole nutrient …

Mapping pregnancy-dependent Sulfhydrome unfolds diverse functions of protein Sulfhydration in human uterine artery

J Bai, F Jiao, AG Salmeron, S Xu, M Xian… - …, 2023 - academic.oup.com
Uterine artery (UA) hydrogen sulfide (H2S) production is augmented in pregnancy and, on
stimulation by systemic/local vasodilators, contributes to pregnancy-dependent uterine …

Sexual dimorphism in selenium metabolism and selenoproteins

LA Seale, AN Ogawa-Wong, MJ Berry - Free Radical Biology and Medicine, 2018 - Elsevier
Sexual dimorphism, the condition in which males and females in a species differ beyond the
morphology of sex organs, delineates critical aspects of the biology of higher eukaryotes …

Hydrogen sulfide and its role in female reproduction

A Pilsova, Z Pilsova, B Klusackova… - Frontiers in Veterinary …, 2024 - frontiersin.org
Hydrogen sulfide (H2S) is a gaseous signaling molecule produced in the body by three
enzymes: cystathionine-β-synthase (CBS), cystathionine-γ-lyase (CSE) and 3 …