Protective effects of PACAP in peripheral organs

D Toth, E Szabo, A Tamas, T Juhasz… - Frontiers in …, 2020 - frontiersin.org
Pituitary adenylate cyclase activating polypeptide (PACAP) is a neuropeptide widely
distributed in the nervous system, where it exerts strong neuroprotective effects. PACAP is …

Effects of PACAP on Schwann cells: focus on nerve injury

G Maugeri, AG D'Amico, G Musumeci… - International Journal of …, 2020 - mdpi.com
Schwann cells, the most abundant glial cells of the peripheral nervous system, represent the
key players able to supply extracellular microenvironment for axonal regrowth and …

Pituitary adenylate cyclase-activating polypeptide (PACAP) in physiological and pathological processes within the gastrointestinal tract: a review

A Karpiesiuk, K Palus - International Journal of Molecular Sciences, 2021 - mdpi.com
Pituitary adenylate cyclase-activating polypeptide (PACAP) is a neuropeptide widely
distributed in the central nervous system (CNS) and many peripheral organs, such as the …

PACAP deficiency as a model of aging

D Reglodi, T Atlasz, E Szabo, A Jungling, A Tamas… - Geroscience, 2018 - Springer
Dysregulation of neuropeptides may play an important role in aging-induced impairments. In
the long list of neuropeptides, pituitary adenylate cyclase–activating polypeptide (PACAP) …

PACAP and VIP neuropeptides' and receptors' effects on appetite, satiety and metabolism

JP Vu, L Luong, D Sanford, S Oh, A Kuc, R Pisegna… - Biology, 2023 - mdpi.com
Simple Summary PACAP and VIP are peptides produced and released in the central and
peripheral nervous systems and in a variety of peripheral organs and tissues. PACAP and …

The functional heterogeneity of PACAP: Stress, learning, and pathology

AK Rajbhandari, JR Barson, MR Gilmartin… - Neurobiology of learning …, 2023 - Elsevier
Pituitary adenylate cyclase-activating peptide (PACAP) is a highly conserved and widely
expressed neuropeptide that has emerged as a key regulator of multiple neural and …

Neuroendocrine mechanism of gastric acid secretion: Historical perspectives and recent developments in physiology and pharmacology

D Chen, SJ Hagen, M Boyce… - Journal of …, 2023 - Wiley Online Library
The physiology of gastric acid secretion is one of the earliest subjects in medical literature
and has been continuously studied since 1833. Starting with the notion that neural …

Changes in ghrelin, substance P and vasoactive intestinal peptide levels in the gastroduodenal mucosa of patients with morbid obesity

U Atas, N Erin, G Tazegul, GO Elpek, B Yildirim - Neuropeptides, 2021 - Elsevier
Aims The aim of the study was to assess changes in levels of substance P (SP), vasoactive
intestinal peptide (VIP) and ghrelin in the gastroduodenal mucosa of obese individuals …

Distribution of PACAP and PAC1 Receptor in the Human Eye

E Patko, E Szabo, D Toth, T Tornoczky… - Journal of Molecular …, 2022 - Springer
Pituitary adenylate cyclase–activating polypeptide (PACAP) is a neuropeptide with
widespread distribution and diverse biological functions. Several studies show that PACAP …

Multimodal role of PACAP in glioblastoma

AG D'Amico, G Maugeri, L Vanella, V Pittalà, D Reglodi… - Brain Sciences, 2021 - mdpi.com
Glioblastoma multiforme (GBM) is the deadliest form of brain tumors. To date, the GBM
therapeutical approach consists of surgery, radiation-therapy and chemotherapy combined …