In Drosophila melanogaster, the causal links among a complex behaviour, single neurons
and single genes can be demonstrated through experimental manipulations. A key player in …

In most animals, the brain controls the body via a set of descending neurons (DNs) that
traverse the neck. DN activity activates, maintains or modulates locomotion and other …

Summary Background After mating, Drosophila females undergo a remarkable phenotypic
switch resulting in decreased sexual receptivity and increased egg laying. Transfer of male …

Neurogenetic analyses in the fruit fly Drosophila melanogaster revealed that gendered
behaviors, including courtship, are underpinned by sexually dimorphic neural circuitries …

Precise genetic manipulation of specific cell types or tissues to pinpoint gene function
requirement is a critical step in studies aimed at unraveling the intricacies of organismal …

Evolution has shaped nervous systems to produce stereotyped behavioural responses to
ethologically relevant stimuli. For example when laying eggs, female Drosophila avoid …

Neurons that participate in sensory processing often display “ON” responses, ie, fire
transiently at the onset of a stimulus. ON transients are widespread, perhaps universal to …

FoxP2 is a highly conserved vertebrate transcription factor known for its importance in
human speech and language production. Disruption of FoxP2 in several vertebrate models …

Abstract Background In Drosophila, male flies require the expression of the male-specific
Fruitless protein (FRU M) within the developing pupal and adult nervous system in order to …

The majority of the neurons in the adult Drosophila thoracic nervous system are produced by
one unpaired and twenty-four bilaterally paired, segmentally reiterated neuroblasts (NBs) …