Non-alcoholic fatty liver disease (NAFLD) has emerged pandemically across the globe and
particularly affects patients with obesity and type 2 diabetes. NAFLD is a complex systemic …

An excess of saturated fatty acids and simple sugars in the diet is a known environmental
risk factor of Alzheimer's disease (AD) but the holistic view of the interacting processes …

Macrophage activation is intimately linked to metabolic reprogramming. Inflammatory (M1)
macrophages are able to sustain inflammatory responses and to kill pathogens, mostly by …

Inflammasomes are large protein complexes that play a major role in sensing inflammatory
signals and triggering the innate immune response. Each inflammasome complex has three …

Background and Purpose Naringenin, a flavonoid compound with strong anti‐inflammatory
activity, attenuated non‐alcoholic fatty liver disease (NAFLD) induced by a methionine …

Psoriasis is a chronic inflammatory skin disease characterized by accelerated tumor
necrosis factor-α/interleukin-23/interleukin-17 axis, hyperproliferation and abnormal …

Macrophages are critical mediators of tissue homeostasis, with the function of tissue
development and repair, but also in defense against pathogens. Tumor-associated …

Obesity is a major public health issue worldwide since it is associated with the development
of chronic comorbidities such as type 2 diabetes, dyslipidemias, atherosclerosis, some …

Triglycerides, phospholipids, and cholesterol are prominent lipid types that serve diverse
biological functions. These lipids act as vital structural components of cell membranes …

Sustained inflammation associated with dysregulated macrophage activation prevents
tissue formation and healing of chronic wounds. Control of inflammation and immune cell …