The dramatic global rise of MDR and XDR Enterobacterales in human medicine forced
clinicians to the reintroduction of colistin as last-resort drug. Meanwhile, colistin is used in …

Antibiotic resistance is one of the greatest public-health challenges worldwide, especially
with regard to Gram-negative bacteria (GNB). Carbapenems are the β-lactam antibiotics of …

Antimicrobial resistance (AMR) is one of the largest global concerns due to its influence in
multiple areas, which is consistent with One Health's concept of close interconnections …

Multidrug-resistant bacteria cause difficult-to-treat infections and pose a risk for modern
medicine. Sources of multidrug-resistant bacteria include hospital, municipal and …

The emergence of carbapenem resistant bacteria (CRB) possesses a remarkable threat to
the health of humans. CRB and carbapenem resistance genes (CRGs) have frequently been …

Colistin resistance has increased due to the increasing and inappropriate use of this
antibiotic. The mechanism involves modification of lipid A with phosphoethanolamine (PEtN) …

Introduction Polymyxins, the cationic lipopeptide antibiotics, are the last line of therapeutics
against the MDR Gram-negative bacterial (GNB) pathogens. Unfortunately, the rising cases …

The objective of this study was to determine the presence and persistence of antimicrobial-
resistant enterobacteria and their clonal distribution in hospital wastewater. A descriptive …

Carbapenemase-producing Klebsiella pneumoniae (CPKP) isolated from influent (I) and
effluent (E) of two wastewater treatment plants, with (S1) or without (S2) hospital …

Biofilm-mediated infections are critical to public health and a leading cause of resistance
among pathogens, amounting to a prolonged hospital stay and increased mortality rate in …