The thalamus is a small, bilateral structure in the diencephalon that integrates signals from
many areas of the CNS. This critical anatomical position allows the thalamus to influence …

Functions of the neocortex depend on its bidirectional communication with the thalamus, via
cortico-thalamo-cortical (CTC) loops. Recent work dissecting the synaptic connectivity in …

Historically, the thalamus has been viewed as little more than a relay, simply transferring
information to key players of the cast, the cortex and hippocampus, without providing any …

The human brain is a complex, adaptive system comprised of billions of cells with trillions of
connections. The interactions between the elements of the system oppose this seemingly …

Inhibitory control is a fundamental mechanism underlying flexible behavior and features in
theories across many areas of cognitive and psychological science. However, whereas …

Humans can recollect past events in details (recollection) and/or know that an object,
person, or place has been encountered before (familiarity). During the last two decades …

Working memory is characterized by neural activity that persists during the retention interval
of delay tasks. Despite the ubiquity of this delay activity across tasks, species and …

Thalamocortical dysrhythmia is a key pathology of chronic neuropathic pain, but few studies
have investigated thalamocortical networks in chronic low back pain (cLBP) given its non …

Interactions between the thalamus and prefrontal cortex (PFC) play a critical role in cognitive
function and arousal. Here, we use anatomical tracing, electrophysiology, optogenetics, and …

A hallmark of non-rapid eye movement sleep is the coordinated interplay of slow oscillations
(SOs) and sleep spindles. Traditionally, a cortico-thalamo-cortical loop is suggested to …