Navigation through the bulk tumour, entry into the blood vasculature, survival in the
circulation, exit at distant sites and resumption of proliferation are all steps necessary for …

Machine learning (ML) refers to a set of automatic pattern recognition methods that have
been successfully applied across various problem domains, including biomedical image …

Bone marrow vascular niches sustain hematopoietic stem cells (HSCs) and are drastically
remodeled in leukemia to support pathological functions. Acute myeloid leukemia (AML) …

It is widely accepted that complex interactions between cancer cells and their surrounding
microenvironment contribute to disease development, chemo-resistance and disease …

The cell membrane is a vital barrier that protects the cell from external damage and is
involved in many biochemical processes. Thus, it is of great significance to label the cell …

Background Cancer is a highly complex disease, which involves the cooperation of tumor
cells with multiple types of host cells and the extracellular matrix. Cancer studies that rely …

Currently, most biological research relies on conventional experimental techniques that
allow only static analyses at certain time points in vitro or ex vivo. However, if one could …

Background The marrow microenvironment and vasculature plays a critical role in regulating
hematopoietic cell recruitment, residence, and maturation. Extensive in vitro and in vivo …

A key predictor for the success of gene-modified T cell therapies for cancer is the
persistence of transferred cells in the patient. The propensity of less differentiated memory T …

Tissues are heterogeneous with respect to cellular and non-cellular components and in the
dynamic interactions between these elements. To study the behaviour and fate of individual …