Sorting nexin (SNX) 9 was first discovered as an endocytic accessory protein involved in
clathrin-mediated endocytosis. However, recent data suggest that SNX9 is a multifunctional …

Selective autophagy is a catabolic route that turns over specific cellular material for
degradation by lysosomes, and whose role in the regulation of innate immunity is largely …

Deoxynivalenol (vomitoxin, DON) is a secondary metabolite produced by Fusarium spp.
fungi and it is one of the most prevalent mycotoxins worldwide. Crop infestation results not …

Evolutionarily conserved genes often play critical roles in organismal physiology. Here, we
describe multiple roles of a previously uncharacterized Class III metallophosphodiesterase …

Sigma 1 Receptor (S1R) is a therapeutic target for a wide spectrum of pathological
conditions ranging from neurodegenerative diseases to cancer and COVID-19. S1R is …

Golgi phosphoprotein 3 (GOLPH3) is a highly conserved peripheral membrane protein
localized to the Golgi apparatus and the cytosol. GOLPH3 binding to Golgi membranes …

Nervous wreck (Nwk) is a conserved F-BAR protein that attenuates synaptic growth and
promotes synaptic function in Drosophila. In an effort to understand how Nwk carries out its …

During cytokinesis, an actomyosin contractile ring drives the separation of the two daughter
cells. A key molecule in this process is the inositol lipid PtdIns (4, 5) P 2, which recruits …

Membrane protrusions are fundamental to cellular functions like migration, adhesion, and
communication and depend upon dynamic reorganization of the cytoskeleton. GAP …

Numerous motors of the Kinesin family contribute to plus-end-directed microtubule transport.
However, almost all transport towards the minus-end of microtubules involves Dynein …