Motivational processes underlie behaviors that enrich the human experience, and
impairments in motivation are commonly observed in psychiatric illness. While motivated …

Compulsion is a cardinal symptom of drug addiction (severe substance use disorder).
However, compulsion is observed in only a small proportion of individuals who repeatedly …

The dopaminergic system plays important roles in neuromodulation, such as motor control,
motivation, reward, cognitive function, maternal, and reproductive behaviors. Dopamine is a …

When people are forced to be isolated from each other, do they crave social interactions? To
address this question, we used functional magnetic resonance imaging to measure neural …

The brain plays a key role in the controls of energy intake and expenditure, and many genes
associated with obesity are expressed in the central nervous system. Technological and …

INTRODUCTION The drive to seek and experience reward is conserved across species and,
in mammals, involves interactions between subcortical dopaminergic systems and limbic …

Dopamine (DA) is a major monoamine neurotransmitter in the brain and has essential roles
in higher functions of the brain. Malfunctions of dopaminergic signaling have been …

Social behaviours in species as diverse as honey bees and humans promote group survival
but often come at some cost to the individual. Although reinforcement of adaptive social …

Music is used to regulate mood and arousal in everyday life and to promote physical and
psychological health and well-being in clinical settings. However, scientific inquiry into the …

In the young of many mammalian species, including humans, a vigorous and highly
rewarding social activity is abundantly expressed, known as social play behaviour. Social …