The hitchhiker's guide to flow chemistry∥

MB Plutschack, B Pieber, K Gilmore… - Chemical …, 2017 - ACS Publications
Flow chemistry involves the use of channels or tubing to conduct a reaction in a continuous
stream rather than in a flask. Flow equipment provides chemists with unique control over …

Bifunctional amine‐squaramides: powerful hydrogen‐bonding organocatalysts for asymmetric domino/cascade reactions

P Chauhan, S Mahajan, U Kaya… - … Synthesis & Catalysis, 2015 - Wiley Online Library
Organocatalytic domino/cascade reactions provide a convenient method for the construction
of complex molecular structures bearing multiple stereocenters in a highly stereoselective …

Green asymmetric organocatalysis

D Krištofíková, V Modrocká, M Mečiarová… - …, 2020 - Wiley Online Library
Asymmetric organocatalysis is becoming one of the main tools for the synthesis of chiral
compounds that are needed as medicines, crop protection agents, and other bioactive …

Flow fine synthesis with heterogeneous catalysts

K Masuda, T Ichitsuka, N Koumura, K Sato… - Tetrahedron, 2018 - Elsevier
In the past few decades, organic reactions under flow conditions have attracted increasing
attention. Flow reactions have a number of advantages over batch reactions in terms of …

Turning on catalysis: incorporation of a hydrogen-bond-donating squaramide moiety into a Zr metal–organic framework

CM McGuirk, MJ Katz, CL Stern… - Journal of the …, 2015 - ACS Publications
Herein, we demonstrate that the incorporation of an acidic hydrogen-bond-donating
squaramide moiety into a porous UiO-67 metal–organic framework (MOF) derivative leads to …

Asymmetric organocatalysis in continuous flow: opportunities for impacting industrial catalysis

I Atodiresei, C Vila, M Rueping - ACS Catalysis, 2015 - ACS Publications
The review highlights the different advantages associated with organocatalytic
transformations performed in continuous-flow systems and presents the reactions which …

Squaramide‐catalyzed asymmetric reactions

BL Zhao, JH Li, DM Du - The Chemical Record, 2017 - Wiley Online Library
Bifunctional squaramides have emerged as powerful hydrogen‐bonding catalysts for
promoting a wide array of useful asymmetric reactions, which provides convenient methods …

Recent advances in asymmetric organocatalyzed conjugate additions to nitroalkenes

DA Alonso, A Baeza, R Chinchilla, C Gómez… - Molecules, 2017 - mdpi.com
The asymmetric conjugate addition of carbon and heteroatom nucleophiles to nitroalkenes
is a very interesting tool for the construction of highly functionalized synthetic building …

Recent advances in continuous-flow organocatalysis for process intensification

C De Risi, O Bortolini, A Brandolese… - Reaction Chemistry & …, 2020 - pubs.rsc.org
Chemistry in continuous-flow continues to attract attention from the community of synthetic
organic chemists due to its now well-recognized benefits including, inter alia, quick reaction …

Reworking organic synthesis for the modern age: Synthetic strategies based on continuous-flow addition and condensation reactions with heterogeneous catalysts

WJ Yoo, H Ishitani, Y Saito, B Laroche… - The Journal of Organic …, 2020 - ACS Publications
While organic synthesis carried out in most laboratories uses batch methods, there is
growing interest in modernizing fine chemical synthesis through continuous-flow processes …