Recent advances of smart materials for ocular drug delivery

X Wang, F Luan, H Yue, C Song, S Wang… - Advanced drug delivery …, 2023 - Elsevier
Owing to the variety and complexity of ocular diseases and the natural ocular barriers, drug
therapy for ocular diseases has significant limitations, such as poor drug targeting to the site …

Unveiling the power of gabapentin-loaded nanoceria with multiple therapeutic capabilities for the treatment of dry eye disease

CJ Yang, A Anand, CC Huang, JY Lai - ACS nano, 2023 - ACS Publications
Dry eye (DE) disease, which is primarily linked to aqueous deficiency, is an escalating
health issue worldwide, mainly due to the widespread use of electronic devices. The major …

The Impressive Anti-Inflammatory Activity of Cerium Oxide Nanoparticles: More than Redox?

F Corsi, G Deidda Tarquini, M Urbani, I Bejarano… - Nanomaterials, 2023 - mdpi.com
Cerium oxide nanoparticles (CNPs) are biocompatible nanozymes exerting multifunctional
biomimetic activities, including superoxide dismutase (SOD), catalase, glutathione …

A Novel Photosynthetic Biohybrid System for Microenvironment Regulation of Diabetes Retinopathy through Continuous Oxygen Supply and Nanozyme Cascade …

L Zhou, K Lan, X Huang, Y Huang, Y Jin… - Advanced Functional …, 2023 - Wiley Online Library
Abstract According to International Diabetes Federation Diabetes Atlas statistics, diabetic
retinopathy (DR) is the leading cause of vision loss in blinding diseases. The underlying …

Retinal Microenvironment‐Protected Rhein‐GFFYE Nanofibers Attenuate Retinal Ischemia‐Reperfusion Injury via Inhibiting Oxidative Stress and Regulating …

Z Zhang, S Peng, T Xu, J Liu, L Zhao, H Xu… - Advanced …, 2023 - Wiley Online Library
Retinal ischemia is involved in the occurrence and development of various eye diseases,
including glaucoma, diabetic retinopathy, and central retinal artery occlusion. To the best of …

Platinum nanozymes counteract photoreceptor degeneration and retina inflammation in a light-damage model of age-related macular degeneration

S Cupini, S Di Marco, L Boselli, A Cavalli, G Tarricone… - ACS …, 2023 - ACS Publications
Degeneration of photoreceptors in age-related macular degeneration (AMD) is associated
with oxidative stress due to the intense aerobic metabolism of rods and cones that if not …

Multifunctional Nanotherapeutics with Long-Acting Release against Macular Degeneration by Minimally Invasive Administration

W Chang, X Lv, J Zhu, JJ Shen, J Yao, Z Liu, Q Chen - ACS nano, 2024 - ACS Publications
Neovascular age-related macular degeneration (AMD), a leading cause of blindness,
requires frequent intravitreal injection of antivascular endothelial growth factor (anti-VEGF) …

Multifunctional hydrogel eye drops for synergistic treatment of ocular inflammatory disease

X Liu, Z Chen, J Bai, X Li, X Chen, Z Li, H Pan, S Li… - ACS …, 2023 - ACS Publications
Uveitis is a complex ocular inflammatory disease with a multifactorial etiology that can result
in blindness. Although corticosteroid eye drops are the primary treatment for anterior uveitis …

Multifunctional cerium oxide nanozyme for synergistic dry eye disease therapy

H Zou, Y Hong, B Xu, M Wang, H Xie… - ACS Applied Materials …, 2024 - ACS Publications
Dry eye disease (DED) is a chronic multifactorial ocular surface disease mainly caused by
the instability of tear film, characterized by a series of ocular discomforts and even visual …

Multifunctional cerium oxide nanozymes with high ocular surface retention for dry eye disease treatment achieved by restoring redox balance

H Zou, Y Hong, B Xu, M Wang, H Xie, Q Lin - Acta Biomaterialia, 2024 - Elsevier
Dry eye disease (DED) is a kind of multifactorial ocular surface disease that displays ocular
discomfort, visual disturbance, and tear film instability. Oxidative stress is a fundamental …