Neuromodulation by the immune system: a focus on cytokines

AF Salvador, KA de Lima, J Kipnis - Nature Reviews Immunology, 2021 - nature.com
Interactions between the immune system and the nervous system have been described
mostly in the context of diseases. More recent studies have begun to reveal how certain …

Somatosensory and autonomic neuronal regulation of the immune response

S Udit, K Blake, IM Chiu - Nature Reviews Neuroscience, 2022 - nature.com
Bidirectional communication between the peripheral nervous system (PNS) and the immune
system is a crucial part of an effective but balanced mammalian response to invading …

Central glucagon-like peptide 1 receptor activation inhibits Toll-like receptor agonist-induced inflammation

CK Wong, BA McLean, LL Baggio, JA Koehler… - Cell Metabolism, 2024 - cell.com
Glucagon-like peptide-1 receptor agonists (GLP-1RAs) exert anti-inflammatory effects
relevant to the chronic complications of type 2 diabetes. Although GLP-1RAs attenuate T cell …

Cerebral dysfunctions caused by sepsis during ageing

T Manabe, MT Heneka - Nature Reviews Immunology, 2022 - nature.com
Systemic inflammation elicited by sepsis can induce an acute cerebral dysfunction known as
sepsis-associated encephalopathy (SAE). Recent evidence suggests that SAE is common …

Mechanisms and therapeutic relevance of neuro-immune communication

SS Chavan, VA Pavlov, KJ Tracey - Immunity, 2017 - cell.com
Active research at the frontiers of immunology and neuroscience has identified multiple
points of interaction and communication between the immune system and the nervous …

Molecular and functional neuroscience in immunity

VA Pavlov, SS Chavan, KJ Tracey - Annual review of …, 2018 - annualreviews.org
The nervous system regulates immunity and inflammation. The molecular detection of
pathogen fragments, cytokines, and other immune molecules by sensory neurons generates …

The vagus nerve in the neuro-immune axis: implications in the pathology of the gastrointestinal tract

B Bonaz, V Sinniger, S Pellissier - Frontiers in immunology, 2017 - frontiersin.org
The vagus nerve (VN) is the longest nerve of the organism and a major component of the
parasympathetic nervous system which constitutes the autonomic nervous system (ANS) …

Bioelectronic medicine: preclinical insights and clinical advances

VA Pavlov, KJ Tracey - Neuron, 2022 - cell.com
The nervous system maintains homeostasis and health. Homeostatic disruptions underlying
the pathobiology of many diseases can be controlled by bioelectronic devices targeting CNS …

Reductions in anti-inflammatory gut bacteria are associated with depression in a sample of young adults

RT Liu, AD Rowan-Nash, AE Sheehan… - Brain, behavior, and …, 2020 - Elsevier
We assessed the gut microbiota of 90 American young adults, comparing 43 participants
with major depressive disorder (MDD) and 47 healthy controls, and found that the MDD …

Critical neurotransmitters in the neuroimmune network

TW Hodo, MTP De Aquino, A Shimamoto… - Frontiers in …, 2020 - frontiersin.org
Immune cells rely on cell-cell communication to specify and fine-tune their responses. They
express an extensive network of cell communication modes, including a vast repertoire of …