Anatomical and physiological alterations of pregnancy

JM Kazma, J van den Anker, K Allegaert… - … of pharmacokinetics and …, 2020 - Springer
The extensive metabolic demands of pregnancy require specific physiological and
anatomical changes. These changes affect almost all organ systems, including the …

Gastrointestinal malabsorption of thyroxine

C Virili, A Antonelli, MG Santaguida… - Endocrine …, 2019 - academic.oup.com
Levothyroxine, a largely prescribed drug with a narrow therapeutic index, is often a lifelong
treatment. The therapeutic efficacy of T4 may be marred by behavioral, pharmacologic, and …

Thyroid hormone therapy for hypothyroidism

B Biondi, DS Cooper - Endocrine, 2019 - Springer
The purpose of this article will be to review the basics of thyroid hormone therapy, including
various thyroid hormone formulations, the institution and monitoring of thyroid hormone …

Optimal thyroid hormone replacement

J Jonklaas - Endocrine reviews, 2022 - academic.oup.com
Hypothyroidism is a common endocrinopathy, and levothyroxine is frequently prescribed.
Despite the basic tenets of initiating and adjusting levothyroxine being agreed on, there are …

Nutritional and health factors affecting the bioavailability of calcium: a narrative review

N Wawrzyniak, J Suliburska - Nutrition Reviews, 2021 - academic.oup.com
Calcium is responsible for the effectiveness of various processes, and its supply in the diet is
necessary for the normal function of the human body. Apart from being an important …

New formulations of levothyroxine in the treatment of hypothyroidism: trick or treat?

EV Nagy, P Perros, E Papini, M Katko, L Hegedüs - Thyroid, 2021 - liebertpub.com
Background: Levothyroxine (LT4) as a medication is used by up to 5.3% of the adult
population. For optimal efficacy, the traditional tablet formulation (LT4tab) requires that …

Pediatric hypothyroidism: diagnosis and treatment

AJ Wassner - Pediatric Drugs, 2017 - Springer
Thyroid hormone has important physiologic functions in nearly every organ system. The
critical role of thyroid hormone in growth and in physical and neurologic development lends …

Interactions in cancer treatment considering cancer therapy, concomitant medications, food, herbal medicine and other supplements

CPJG Wolf, T Rachow, T Ernst, A Hochhaus… - Journal of Cancer …, 2022 - Springer
Purpose The aim of our study was to analyse the frequency and severity of different types of
potential interactions in oncological outpatients' therapy. Therefore, medications, food and …

Levothyroxine therapy in gastric malabsorptive disorders

C Virili, N Brusca, S Capriello… - Frontiers in Endocrinology, 2021 - frontiersin.org
Oral levothyroxine sodium is absorbed in the small intestine, mainly in the jejunum and the
ileum being lower the absorption rate at duodenal level. The time interval between the …

Evaluating health outcomes in the treatment of hypothyroidism

MD Ettleson, M Papaleontiou - Frontiers in endocrinology, 2022 - frontiersin.org
Clinical hypothyroidism is defined by the inadequate production of thyroid hormone from the
thyroid gland to maintain normal organ system functions. For nearly all patients with clinical …