Autonomic control of ventricular function in health and disease: current state of the art

VYH van Weperen, CM Ripplinger… - Clinical Autonomic …, 2023 - Springer
Purpose Cardiac autonomic dysfunction is one of the main pillars of cardiovascular
pathophysiology. The purpose of this review is to provide an overview of the current state of …

Stellate ganglia and cardiac sympathetic overactivation in heart failure

YL Li - International journal of molecular sciences, 2022 - mdpi.com
Heart failure (HF) is a major public health problem worldwide, especially coronary heart
disease (myocardial infarction)-induced HF with reduced ejection fraction (HFrEF), which …

Neuropeptide Y is elevated in heart failure and is an independent predictor of outcomes

K McDowell, C Adamson, C Jackson… - European Journal of …, 2024 - Wiley Online Library
Abstract Aims Neuropeptide Y (NPY) is the most abundant neuropeptide found in the heart
and is released alongside norepinephrine following prolonged sympathetic activation, a …

From classic to modern prognostic biomarkers in patients with acute myocardial infarction

C Stătescu, L Anghel, BS Tudurachi, A Leonte… - International Journal of …, 2022 - mdpi.com
Despite all the important advances in its diagnosis and treatment, acute myocardial
infarction (AMI) is still one of the most prominent causes of morbidity and mortality …

[HTML][HTML] MINOCA biomarkers: Non-atherosclerotic aspects

X Xu, G Zhang, Z Li, D Li, R Chen, C Huang, Y Li… - Clinica Chimica …, 2023 - Elsevier
Myocardial infarction in the absence of obstructive coronary artery disease (MINOCA) is an
important subtype of myocardial infarction. Although comprising less than 50% stenosis in …

Pathophysiology and outcomes of endothelium function in coronary microvascular diseases: A systematic review of randomized controlled trials and multicenter study

SS Avtaar Singh, F Nappi - Biomedicines, 2022 - mdpi.com
Background: Coronary macrovascular disease is a concept that has been well-studied
within the literature and has long been the subject of debates surrounding coronary artery …

Circulating noradrenaline leads to release of neuropeptide Y from cardiac sympathetic nerve terminals via activation of β‐adrenergic receptors

VYH van Weperen, JD Hoang, NR Jani… - The Journal of …, 2024 - Wiley Online Library
Cardiac disease is marked by sympathoexcitation and elevated levels of noradrenaline (NA)
and cotransmitter neuropeptide Y (NPY). Increased NPY levels are associated with a greater …

[HTML][HTML] Relation of plasma neuropeptide-Y with myocardial function and infarct severity in acute ST-elevation myocardial infarction

C Tiller, M Reindl, M Holzknecht, I Lechner… - European Journal of …, 2024 - Elsevier
Background Acute myocardial infarction is associated with the release of the co-transmitter
neuropeptide-Y (NPY). NPY acts as a potent vasoconstrictor and is associated with …

Molecular and cellular neurocardiology in heart disease

BA Habecker, DM Bers, SJ Birren… - The Journal of …, 2024 - Wiley Online Library
This paper updates and builds on a previous White Paper in this journal that some of us
contributed to concerning the molecular and cellular basis of cardiac neurobiology of heart …

Bayliss Starling Prize Lecture 2023: Neuropeptide‐Y being 'unsympathetic'to the broken hearted

B Bussmann, T Ayagama, K Liu, D Li… - The Journal of …, 2024 - Wiley Online Library
Abstract William Bayliss and Ernest Starling are not only famous as pioneers in
cardiovascular physiology, but also responsible for the discovery of the first hormone (from …