Ribosomal control in RNA virus-infected cells

X Wang, J Zhu, D Zhang, G Liu - Frontiers in Microbiology, 2022 - frontiersin.org
Viruses are strictly intracellular parasites requiring host cellular functions to complete their
reproduction cycle involving virus infection of host cell, viral genome replication, viral protein …

Direct-acting antivirals and host-targeting approaches against enterovirus B infections: recent advances

C Tammaro, M Guida, F Appetecchia, M Biava… - Pharmaceuticals, 2023 - mdpi.com
Enterovirus B (EV-B)-related diseases, which can be life threatening in high-risk
populations, have been recognized as a serious health problem, but their clinical treatment …

A Copper nanoparticles-based polymeric spray coating: Nanoshield against Sars-Cov-2

I Foffa, P Losi, P Quaranta, A Cara… - Journal of Applied …, 2022 - journals.sagepub.com
Face masks are an effective protection tool to prevent bacterial and viral transmission.
However, commercial face masks contain filters made of materials that are not capable of …

Molecular docking and molecular dynamics simulations discover curcumin analogue as a plausible dual inhibitor for SARS-CoV-2

S Rampogu, G Lee, JS Park, KW Lee… - International Journal of …, 2022 - mdpi.com
Recently, the world has been witnessing a global pandemic with no effective therapeutics
yet, while cancer continues to be a major disease claiming many lives. The natural …

Targeting host DEAD-box RNA helicase DDX3X for treating viral infections

PT Winnard Jr, F Vesuna, V Raman - Antiviral research, 2021 - Elsevier
Abstract DDX3X or DDX3, a member of the DEAD (asp, glu, ala, asp) box RNA helicase
family of proteins, is a multifunctional protein, which is usurped by several viruses and is vital …

DEAD-box helicase DDX3X as a host target against emerging viruses: New insights for medicinal chemical approaches

A Brai, CI Trivisani, F Poggialini… - Journal of Medicinal …, 2022 - ACS Publications
In recent years, globalization, global warming, and population aging have contributed to the
spread of emerging viruses, such as coronaviruses (COVs), West Nile (WNV), Dengue …

Human neural stem cell systems to explore pathogen-related neurodevelopmental and neurodegenerative disorders

M Baggiani, MT Dell'Anno, M Pistello, L Conti… - Cells, 2020 - mdpi.com
Building and functioning of the human brain requires the precise orchestration and
execution of myriad molecular and cellular processes, across a multitude of cell types and …

RK-33, a small molecule inhibitor of host RNA helicase DDX3, suppresses multiple variants of SARS-CoV-2

F Vesuna, I Akhrymuk, A Smith, PT Winnard Jr… - Frontiers in …, 2022 - frontiersin.org
SARS-CoV-2, the virus behind the deadly COVID-19 pandemic, continues to spread globally
even as vaccine strategies are proving effective in preventing hospitalizations and deaths …

[HTML][HTML] Broad-spectrum virucidal activity of a hydroalcoholic extract of grape pomace

E Iacono, C Di Marzo, M Di Stasi, E Cioni… - Bioresource Technology …, 2024 - Elsevier
Grape pomace is a by-product of winemaking often disposed of before full exploitation.
Indeed, this natural product holds great potential for sustainable utilization. In this study …

One-step silver coating of polypropylene surgical mask with antibacterial and antiviral properties

IV Ferrari, G Giuntoli, A Pisani, A Cavallo, P Mazzetti… - Heliyon, 2024 - cell.com
Face masks can filter droplets containing viruses and bacteria minimizing the transmission
and spread of respiratory pathogens but are also an indirect source of microbes …