Zinc as a gatekeeper of immune function
I Wessels, M Maywald, L Rink - Nutrients, 2017 - mdpi.com
After the discovery of zinc deficiency in the 1960s, it soon became clear that zinc is essential
for the function of the immune system. Zinc ions are involved in regulating intracellular …
for the function of the immune system. Zinc ions are involved in regulating intracellular …
Zinc signals and immunity
M Maywald, I Wessels, L Rink - International journal of molecular sciences, 2017 - mdpi.com
Zinc homeostasis is crucial for an adequate function of the immune system. Zinc deficiency
as well as zinc excess result in severe disturbances in immune cell numbers and activities …
as well as zinc excess result in severe disturbances in immune cell numbers and activities …
Divergent roles for the gut intraepithelial lymphocyte GLP-1R in control of metabolism, microbiota, and T cell-induced inflammation
Gut intraepithelial lymphocytes (IELs) are thought to calibrate glucagon-like peptide 1 (GLP-
1) bioavailability, thereby regulating systemic glucose and lipid metabolism. Here, we show …
1) bioavailability, thereby regulating systemic glucose and lipid metabolism. Here, we show …
RNA-binding proteins in immune regulation: a focus on CCCH zinc finger proteins
M Fu, PJ Blackshear - Nature Reviews Immunology, 2017 - nature.com
Nearly 60 CCCH zinc finger proteins have been identified in humans and mice. These
proteins are involved in the regulation of multiple steps of RNA metabolism, including mRNA …
proteins are involved in the regulation of multiple steps of RNA metabolism, including mRNA …
Mammalian Rho GTPases: new insights into their functions from in vivo studies
SJ Heasman, AJ Ridley - Nature reviews Molecular cell biology, 2008 - nature.com
Rho GTPases are key regulators of cytoskeletal dynamics and affect many cellular
processes, including cell polarity, migration, vesicle trafficking and cytokinesis. These …
processes, including cell polarity, migration, vesicle trafficking and cytokinesis. These …
Protein tyrosine phosphatases in the human genome
Tyrosine phosphorylation is catalyzed by protein tyrosine kinases, which are represented by
90 genes in the human genome. Here, we present the set of 107 genes in the human …
90 genes in the human genome. Here, we present the set of 107 genes in the human …
Bat3 promotes T cell responses and autoimmunity by repressing Tim-3–mediated cell death and exhaustion
M Rangachari, C Zhu, K Sakuishi, S Xiao, J Karman… - Nature medicine, 2012 - nature.com
T cell immunoglobulin and mucin domain–containing 3 (Tim-3) is an inhibitory receptor that
is expressed on exhausted T cells during infection with HIV-1 and hepatitis C virus. By …
is expressed on exhausted T cells during infection with HIV-1 and hepatitis C virus. By …
Localized effects of cAMP mediated by distinct routes of protein kinase A
K Taskén, EM Aandahl - Physiological reviews, 2004 - journals.physiology.org
Taskén, Kjetil, and Einar Martin Aandahl. Localized Effects of cAMP Mediated by Distinct
Routes of Protein Kinase A. Physiol Rev 84: 137–167, 2004; 10.1152/physrev. 00021.2003 …
Routes of Protein Kinase A. Physiol Rev 84: 137–167, 2004; 10.1152/physrev. 00021.2003 …
Prostaglandin E2–EP4 signaling promotes immune inflammation through TH1 cell differentiation and TH17 cell expansion
Two distinct helper T (TH) subsets, TH1 and TH17, mediate tissue damage and inflammation
in animal models of various immune diseases such as multiple sclerosis, rheumatoid …
in animal models of various immune diseases such as multiple sclerosis, rheumatoid …
Multi-walled carbon nanotubes induce T lymphocyte apoptosis
Carbon nanotubes are a man-made form of carbon that did not exist in our environment until
very recently. Due to their unique chemical, physical, optical, and magnetic properties …
very recently. Due to their unique chemical, physical, optical, and magnetic properties …