Over 1000 tools reveal trends in the single-cell RNA-seq analysis landscape
Recent years have seen a revolution in single-cell RNA-sequencing (scRNA-seq)
technologies, datasets, and analysis methods. Since 2016, the scRNA-tools database has …
technologies, datasets, and analysis methods. Since 2016, the scRNA-tools database has …
[HTML][HTML] Spatially resolved transcriptomics: a comprehensive review of their technological advances, applications, and challenges
The ability to explore life kingdoms is largely driven by innovations and breakthroughs in
technology, from the invention of the microscope 350 years ago to the recent emergence of …
technology, from the invention of the microscope 350 years ago to the recent emergence of …
Exponential scaling of single-cell RNA-seq in the past decade
Measurement of the transcriptomes of single cells has been feasible for only a few years, but
it has become an extremely popular assay. While many types of analysis can be carried out …
it has become an extremely popular assay. While many types of analysis can be carried out …
Spatiotemporal dynamics of molecular pathology in amyotrophic lateral sclerosis
Paralysis occurring in amyotrophic lateral sclerosis (ALS) results from denervation of
skeletal muscle as a consequence of motor neuron degeneration. Interactions between …
skeletal muscle as a consequence of motor neuron degeneration. Interactions between …
The human cell atlas
A Regev, SA Teichmann, ES Lander, I Amit, C Benoist… - elife, 2017 - elifesciences.org
The recent advent of methods for high-throughput single-cell molecular profiling has
catalyzed a growing sense in the scientific community that the time is ripe to complete the …
catalyzed a growing sense in the scientific community that the time is ripe to complete the …
[HTML][HTML] The human tumor atlas network: charting tumor transitions across space and time at single-cell resolution
O Rozenblatt-Rosen, A Regev, P Oberdoerffer, T Nawy… - Cell, 2020 - cell.com
Crucial transitions in cancer—including tumor initiation, local expansion, metastasis, and
therapeutic resistance—involve complex interactions between cells within the dynamic …
therapeutic resistance—involve complex interactions between cells within the dynamic …
Integrative methods and practical challenges for single-cell multi-omics
Fast-developing single-cell multimodal omics (scMulti-omics) technologies enable the
measurement of multiple modalities, such as DNA methylation, chromatin accessibility, RNA …
measurement of multiple modalities, such as DNA methylation, chromatin accessibility, RNA …
SM-Omics is an automated platform for high-throughput spatial multi-omics
The spatial organization of cells and molecules plays a key role in tissue function in
homeostasis and disease. Spatial transcriptomics has recently emerged as a key technique …
homeostasis and disease. Spatial transcriptomics has recently emerged as a key technique …
Spatial host–microbiome sequencing reveals niches in the mouse gut
B Lötstedt, M Stražar, R Xavier, A Regev… - Nature …, 2024 - nature.com
Mucosal and barrier tissues, such as the gut, lung or skin, are composed of a complex
network of cells and microbes forming a tight niche that prevents pathogen colonization and …
network of cells and microbes forming a tight niche that prevents pathogen colonization and …
Method and product for localized or spatial detection of nucleic acid in a tissue sample
J Frisen, P Ståhl, J Lundeberg - US Patent 10,030,261, 2018 - Google Patents
The present invention relates to methods and products for the localized or spatial detection
of nucleic acid in a tissue sample and in particular to a method for localized detection of …
of nucleic acid in a tissue sample and in particular to a method for localized detection of …