Towards a deeper understanding of the vaginal microbiota

M France, M Alizadeh, S Brown, B Ma, J Ravel - Nature microbiology, 2022 - nature.com
The human vaginal microbiota is a critical determinant of vaginal health. These communities
live in close association with the vaginal epithelium and rely on host tissues for resources …

Vaginal microbiota and the potential of Lactobacillus derivatives in maintaining vaginal health

WJY Chee, SY Chew, LTL Than - Microbial cell factories, 2020 - Springer
Human vagina is colonised by a diverse array of microorganisms that make up the normal
microbiota and mycobiota. Lactobacillus is the most frequently isolated microorganism from …

Contribution of Lactobacillus iners to Vaginal Health and Diseases: A Systematic Review

N Zheng, R Guo, J Wang, W Zhou… - Frontiers in cellular and …, 2021 - frontiersin.org
Lactobacillus iners, first described in 1999, is a prevalent bacterial species of the vaginal
microbiome. As L. iners does not easily grow on de Man-Rogosa-Sharpe agar, but can grow …

Tumor-resident Lactobacillus iners confer chemoradiation resistance through lactate-induced metabolic rewiring

LE Colbert, MB El Alam, R Wang, T Karpinets, D Lo… - Cancer Cell, 2023 - cell.com
Tumor microbiota can produce active metabolites that affect cancer and immune cell
signaling, metabolism, and proliferation. Here, we explore tumor and gut microbiome …

Advances in understanding the human urinary microbiome and its potential role in urinary tract infection

ML Neugent, NV Hulyalkar, VH Nguyen, PE Zimmern… - MBio, 2020 - Am Soc Microbiol
Recent advances in the analysis of microbial communities colonizing the human body have
identified a resident microbial community in the human urinary tract (UT). Compared to many …

[HTML][HTML] Deciphering the complex interplay between microbiota, HPV, inflammation and cancer through cervicovaginal metabolic profiling

ZE Ilhan, P Łaniewski, N Thomas, DJ Roe… - …, 2019 - thelancet.com
Background Dysbiotic vaginal microbiota have been implicated as contributors to persistent
HPV-mediated cervical carcinogenesis and genital inflammation with mechanisms …

Cysteine dependence of Lactobacillus iners is a potential therapeutic target for vaginal microbiota modulation

SM Bloom, NA Mafunda, BM Woolston… - Nature …, 2022 - nature.com
Vaginal microbiota composition affects many facets of reproductive health. Lactobacillus
iners-dominated microbial communities are associated with poorer outcomes, including …

Host and microbiome interplay shapes the vaginal microenvironment

MS Kwon, HK Lee - Frontiers in immunology, 2022 - frontiersin.org
The female reproductive tract harbors a unique microbiome, especially the vagina. The
human vaginal microbiome exhibits a low diversity and is dominated by Lactobacillus …

Crosstalk between female gonadal hormones and vaginal microbiota across various phases of women's gynecological lifecycle

H Kaur, M Merchant, MM Haque… - Frontiers in microbiology, 2020 - frontiersin.org
Functional equilibrium between vaginal microbiota and the host is important for maintaining
gynecological and reproductive health. Apart from host genetics, infections, changes in diet …

Structural variations of vaginal and endometrial microbiota: hints on female infertility

L Riganelli, V Iebba, M Piccioni, I Illuminati… - Frontiers in cellular …, 2020 - frontiersin.org
Microbiota are microorganismal communities colonizing human tissues exposed to the
external environment, including the urogenital tract. The bacterial composition of the vaginal …