CRISPR/Cas12a-based technology: A powerful tool for biosensing in food safety

Z Mao, R Chen, X Wang, Z Zhou, Y Peng, S Li… - Trends in Food Science …, 2022 - Elsevier
Background In the context of the current pandemic caused by the novel coronavirus,
molecular detection is not limited to the clinical laboratory, but also faces the challenge of …

CRISPR-Cas systems for diagnosing infectious diseases

A Kostyusheva, S Brezgin, Y Babin, I Vasilyeva… - Methods, 2022 - Elsevier
Infectious diseases are a global health problem affecting billions of people. Developing
rapid and sensitive diagnostic tools is key for successful patient management and curbing …

A critical review of microfluidic systems for CRISPR assays

AS Avaro, JG Santiago - Lab on a Chip, 2023 - pubs.rsc.org
Reviewed are nucleic acid detection assays that incorporate clustered regularly interspaced
short palindromic repeats (CRISPR)-based diagnostics and microfluidic devices and …

Recent improvements in CRISPR-based amplification-free pathogen detection

J Zhang, H Lv, L Li, M Chen, D Gu, J Wang… - Frontiers in …, 2021 - frontiersin.org
Molecular diagnostic (MDx) methods directly detect target nucleic acid sequences and are
therefore an important approach for precise diagnosis of pathogen infection. In comparison …

CRISPR/Cas and Argonaute-powered lateral flow assay for pathogens detection

Y Li, L Zhao, L Ma, Y Bai, F Feng - Critical Reviews in Food …, 2024 - Taylor & Francis
Pathogens contamination is a pressing global public issue that has garnered significant
attention worldwide, especially in light of recent outbreaks of foodborne illnesses …

Insight into the natural regulatory mechanisms and clinical applications of the CRISPR-Cas system

H Cheng, H Deng, D Ma, M Gao, Z Zhou, H Li, S Liu… - Heliyon, 2024 - cell.com
CRISPR-Cas, the adaptive immune system exclusive to prokaryotes, confers resistance
against foreign mobile genetic elements. The CRISPR-Cas system is now being exploited …

Recent advances and challenges of the use of the CRISPR/Cas system as a non-nucleic acid molecular diagnostic

J Zhou, X Ren, X Wang, Z Li, CJ Xian - Heliyon, 2023 - cell.com
The clustered regularly interspaced short palindromic DNA sequence repeats (CRISPR) and
CRISPR-associated (Cas)(CRISPR/Cas) systems are currently applied not only as a gene …

[HTML][HTML] Advances in traumatic brain injury biomarkers

K Nishimura, JG Cordeiro, AI Ahmed, S Yokobori… - Cureus, 2022 - ncbi.nlm.nih.gov
Traumatic brain injury (TBI) is increasingly a major cause of disability across the globe. The
current methods of diagnosis are inadequate at classifying patients and prognosis. TBI is a …

CRISPR/Cas-based nucleic acid detection strategies: Trends and challenges

J Zhou, Z Li, JS Olajide, G Wang - Heliyon, 2024 - cell.com
CRISPR/Cas systems have become integral parts of nucleic acid detection apparatus and
biosensors. Various CRISPR/Cas systems such as CRISPR/Cas9, CRISPR/Cas12 …

Development of CRISPR-mediated nucleic acid detection technologies and their applications in the livestock industry

X Zhang - Genes, 2022 - mdpi.com
The rapid rate of virus transmission and pathogen mutation and evolution highlight the
necessity for innovative approaches to the diagnosis and prevention of infectious diseases …