Dendrimers as pharmaceutical excipients: synthesis, properties, toxicity and biomedical applications

A Santos, F Veiga, A Figueiras - Materials, 2019 - mdpi.com
The European Medicines Agency (EMA) and the Current Good Manufacturing Practices
(cGMP) in the United States of America, define excipient as the constituents of the …

Pathogenesis and treatment of multiple myeloma

P Yang, Y Qu, M Wang, B Chu, W Chen, Y Zheng… - MedComm, 2022 - Wiley Online Library
Multiple myeloma (MM) is the second‐ranking malignancy in hematological tumors. The
pathogenesis of MM is complex with high heterogeneity, and the development of the …

Low-intensity focused ultrasound-assisted dox-piperine amplified therapy on anaplastic thyroid carcinoma by hybird tumor-targeting nanoparticles

L Zhu, Q Wang, G Sui, D Teng, H Li, Y Wang… - Journal of Drug Delivery …, 2023 - Elsevier
Therapies against anaplastic thyroid carcinoma (ATC) have been sticking in the
predicament of multiple drug resistance (MDR). To address multiple drug resistance and …

Which dendrimer to attain the desired properties? Focus on Phosphorhydrazone Dendrimers

AM Caminade, JP Majoral - Molecules, 2018 - mdpi.com
Among the six Critical Nanoscale Design Parameters (CNDPs) proposed by Prof. Donald A.
Tomalia, this review illustrates the influence of the sixth one, which concerns the elemental …

Exploring the anti-myeloma potential of composite nanoparticles As4S4/Fe3O4: Insights from in vitro, ex vivo and in vivo studies

D Cholujova, ZL Bujnakova, E Dutkova… - … , Biology and Medicine, 2024 - Elsevier
Given the profound multiple myeloma (MM) heterogeneity in clonal proliferation of malignant
plasma cells (PCs) and anti-MM therapeutic potential of nanotherapies, it is inevitable to …

Radionanotheranostics for breast cancer diagnosis and therapy: Recent advances and future opportunities

AK Mehata, MK Viswanadh, VR Solomon… - … Nanomedicine for Breast …, 2022 - Elsevier
Breast cancer is one of the highest causes of mortality in women globally. Poor tumor
permeability, multidrug resistance, delayed diagnosis, and complications associated with …

PPI/CNT nanocomposite for novel high capacity removal of the toxic heavy metals, Hg, Pb and Ni from water

B Hayati, A Maleki, F Najafi, R Rezaee… - Desalination and Water …, 2020 - Elsevier
In this study, a new methodology is reported for the preparation of polypropylene imine
dendrimer functionalized carbon nanotubes and a PPI/CNT nanocomposite. The PPI/CNT …

[PDF][PDF] Nanomaterials modification by dendrimers-A review

M Pawlaczyk, J Kurczewska, G Schroeder - World Journal of Research and …, 2018 - wjrr.org
Following review summarizes the application of dendrimer-functionalized hybrid
nanomaterials. Dendrimers are nano-sized, radially symmetric molecules with well-defined …

[HTML][HTML] Chemotherapy Release From Bortezomib-Impregnated Polymethylmethacrylate-Coated Intramedullary Nails: A Novel In Vitro Study for a Local …

E Ren, W Ren, AC Collins, A Robinson, R Vaidya - Cureus, 2024 - ncbi.nlm.nih.gov
Bortezomib (BAN) is a proteasome inhibitor approved for the treatment of multiple myeloma
and lymphoma. Despite its efficacy in various tumor models, systemic administration can …

Integration of Dendrimer‐Based Delivery Technologies with Computational Pharmaceutics and Their Potential in the Era of Nanomedicine

KR Tupally, P Seal, P Pandey… - … ‐AI and Modeling in …, 2024 - Wiley Online Library
Dendrimers are synthetic macromolecules of either symmetric or asymmetric branching
architecture that are relatively monodispersed nanomaterials and can accommodate …