Abstract γδ T cells are a unique T cell subpopulation that are rare in secondary lymphoid
organs but enriched in many peripheral tissues, such as the skin, intestines and lungs. By …

Immunity to malaria has been linked to the availability and function of helper CD4+ T cells,
cytotoxic CD8+ T cells and γδ T cells that can respond to both the asymptomatic liver stage …

Crohn's disease (CD) is a chronic transmural inflammation of intestinal segments caused by
dysregulated interaction between microbiome and gut immune system. Here, we profile, via …

T lymphocytes comprise cells expressing either an αβ or a γδ TCR. The riddle how αβ TCRs
are triggered by specific peptides presented in the context of MHC was elucidated some …

Experimental autoimmune encephalomyelitis is a model for multiple sclerosis. Here we
show that induction generates successive waves of clonally expanded CD4+, CD8+ and γδ+ …

Gamma-delta (γδ) T cells recognize antigens in a major histocompatibility complex (MHC)
independent and have cytotoxic capability. Human immunodeficiency virus (HIV) infection …

γδ T cells are an abundant T cell population at the mucosa and are important in providing
immune surveillance as well as maintaining tissue homeostasis. However, despite γδ T …

As interest in γδ T cells grows rapidly, what key points are emerging, and where is caution
warranted? γδ T cells fulfill critical functions, as reflected in associations with vaccine …

Abstract γδ T cells have been retained as a lineage over the majority of vertebrate evolution,
are able to respond to immune challenges in unique ways, and are of increasing therapeutic …

Epithelial and mucosal barriers are critical interfaces physically separating the body from the
outside environment and are the tissues most exposed to microorganisms and potential …