Radiation‐induced cardiovascular disease: review of an underrecognized pathology

E Belzile‐Dugas, MJ Eisenberg - Journal of the American Heart …, 2021 - Am Heart Assoc
Radiation therapy demonstrates a clear survival benefit in the treatment of several
malignancies. However, cancer survivors can develop a wide array of cardiotoxic …

Prevention, Diagnosis, and Management of Radiation-Associated Cardiac Disease: JACC Scientific Expert Panel

MY Desai, S Windecker, P Lancellotti, JJ Bax… - Journal of the American …, 2019 - jacc.org
Radiation-associated cardiac disease, a heterogeneous and complex disease, manifests
years or even decades following radiation exposure to the chest. It is associated with a …

Advanced imaging modalities to monitor for cardiotoxicity

A Seraphim, M Westwood, AN Bhuva, T Crake… - … Treatment Options in …, 2019 - Springer
Opinion statement Early detection and treatment of cardiotoxicity from cancer therapies is
key to preventing a rise in adverse cardiovascular outcomes in cancer patients. Over …

Valvular heart disease and cardiomyopathy: reappraisal of their interplay

N Ajmone Marsan, F Graziani, MC Meucci… - Nature Reviews …, 2024 - nature.com
Cardiomyopathies and valvular heart diseases are typically considered distinct diagnostic
categories with dedicated guidelines for their management. However, the interplay between …

Transcatheter compared with surgical aortic valve replacement in patients with previous chest-directed radiation therapy

F Yazdchi, SA Hirji, A Nohria, E Percy, M Harloff… - Cardio Oncology, 2021 - jacc.org
Background Cardiac surgery for radiation-induced valvular disease is associated with
adverse outcomes. Transcatheter aortic valve replacement (TAVR) is increasingly used in …

Transcatheter versus surgical aortic valve replacement in patients with prior mediastinal radiation

A Elbadawi, A Albaeni, IY Elgendy… - Cardiovascular …, 2020 - jacc.org
Objectives This study sought to evaluate the trends and outcomes of transcatheter aortic
valve replacement (TAVR) versus surgical aortic valve replacement (SAVR) among patients …

Outcomes of patients with severe symptomatic aortic valve stenosis after chest radiation: transcatheter versus surgical aortic valve replacement

D Zhang, W Guo, MA Al‐Hijji… - Journal of the …, 2019 - Am Heart Assoc
Background Patients with symptomatic severe aortic stenosis and a history of chest radiation
therapy represent a complex and challenging cohort. It is unknown how transcatheter aortic …

Outcomes of patients with mediastinal radiation-associated mitral valve disease undergoing cardiac surgery

E Donnellan, A Alashi, DR Johnston, AM Gillinov… - Circulation, 2019 - Am Heart Assoc
CORRESPONDENCE surgery and concomitant operations, higher Society of Thoracic
Surgeons score (hazard ratio, 1.05; 95% CI, 1.02–1.08) was associated with higher longer …

TAVR in cancer patients: comprehensive review, meta-analysis, and meta-regression

K Marmagkiolis, DJ Monlezun, M Cilingiroglu… - Frontiers in …, 2021 - frontiersin.org
Objectives: This study sought to systematically analyze the available clinical evidence on
TAVR therapy in cancer patients with symptomatic severe AS. Background: Aortic stenosis is …

Short-term outcomes of transcatheter versus isolated surgical aortic valve replacement for mediastinal radiation-associated severe aortic stenosis

V Nauffal, C Bay, PB Shah… - Circulation …, 2021 - Am Heart Assoc
Background: Surgical aortic valve replacement (SAVR) is associated with adverse outcomes
in patients with radiation-associated aortic stenosis. Transcatheter aortic valve replacement …